{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:27:57Z","timestamp":1787772477568,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      We report a 52-year-old man who presented with erythroderma and nodular lesions on face manifesting as \u201cLeonine facies\u201d. He had impaired sensation over the face and was initially diagnosed to have lepromatous leprosy and was treated with antileprosy drugs. Investigations showed a total Leukocyte count of 550 X 10\n                      <jats:sup>9<\/jats:sup>\n                      \/l with 90% atypical lymphoid cells with prominent central nucleolus suggestive of prolymphocytes. On flow cytometry, these cells were positive for cytoplasmic CD3, CD2, CD5, CD7, CD4, and CD38 (dim) and were negative for CD1a and TdT and diagnosis of T-prolymphocytic leukemia was made.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpm.ijpm_301_20","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T04:19:44Z","timestamp":1717042784000},"page":"817-819","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Leonine facies"],"prefix":"10.4103","volume":"64","author":[{"given":"Faheema","family":"Hasan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yatendra","family":"Parashar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram N.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Kashyap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-38-20240829","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1365-2141.1974.tb06769.x","article-title":"Prolymphocytic leukemia","volume":"27","author":"Galton","year":"1974","journal-title":"Br J Hematol"},{"key":"R2-38-20240829","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1182\/blood-2016-01-643569","article-title":"The 2016 revision of the. 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Groupe Francais d'Hematologic cellulaire","volume":"103","author":"Garand","year":"1998","journal-title":"Br J Hematol"},{"key":"R8-38-20240829","doi-asserted-by":"crossref","first-page":"631","DOI":"10.4103\/0019-5154.143573","article-title":"Animal eponyms in dermatology","volume":"59","author":"Jindal","year":"2014","journal-title":"Indian J Dermatol"},{"key":"R9-38-20240829","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1440-0960.2009.00560.x","article-title":"Sezary syndrome presenting with 'leonine facies'","volume":"50","author":"Naseem","year":"2009","journal-title":"Australas J Dermatol"},{"key":"R10-38-20240829","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0733-8635(18)30190-6","article-title":"Leukemia cutis","volume":"12","author":"Ratnam","year":"1994","journal-title":"Dermatol Clin"},{"key":"R11-38-20240829","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jaad.2015.09.017","article-title":"Leonine facies (LF) and mycosis fungoides (MF): A single centre study and systematic review of literature","volume":"73","author":"Brown","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"R12-38-20240829","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s12288-008-0043-6","article-title":"T-cell prolymphocytic leukemia: A report of two cases with review of the literature","volume":"24","author":"Naseem","year":"2008","journal-title":"Indian J Hematol Blood Transf"},{"key":"R13-38-20240829","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1182\/blood-2012-01-380139","article-title":"How I treat prolymphocytic leukemia","volume":"120","author":"Dearden","year":"2015","journal-title":"Blood"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_301_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:49:14Z","timestamp":1787770154000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_301_20"}},"subtitle":["A unique presentation of T-prolymphocytic leukemia"],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_301_20","relation":{},"ISSN":["0377-4929"],"issn-type":[{"value":"0377-4929","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}