{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:30:58Z","timestamp":1787070658315,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"\n \n \n Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare adnexal tumor with a predilection for the skin of the eyelid. It has also been reported in other areas of the face. Extra facial location has rarely been reported. They are twice as common in the females as compared to men and frequently affect the elderly between 50 and 80 years of age. It is a low-grade carcinoma with no reported cases of metastases, although a few cases with recurrences have been reported. Since it was first described by Flieder\n et al<\/jats:italic>\n . in 1997, fewer than 60 cases have been reported in the literature. We describe one such case of EMPSGC in an adult male occurring at an unusual location, the peno-scrotal junction with systemic metastases to bilateral inguinal and iliac lymph nodes, multiple bones, and pancreas. Unlike previously reported cases, our patient worsened rapidly and succumbed to the disease six months after initiation of chemotherapy and radiotherapy. To the best of our knowledge, this is the first reported case of its kind in modern published literature.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijpm.ijpm_342_19","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T04:04:25Z","timestamp":1717041865000},"page":"180-182","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Endocrine mucin-producing sweat gland carcinoma of the peno-scrotum with systemic metastases"],"prefix":"10.4103","volume":"64","author":[{"given":"Milap","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambreen","family":"Aman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Srinivaas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Gudipati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja","family":"Chavali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-38-20240829","first-page":"6343709","article-title":"Endocrine mucin-producing sweat gland carcinoma, a histological challenge","volume":"2017","author":"Brett","year":"2017","journal-title":"Case Rep Pathol"},{"key":"R2-38-20240829","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1097\/01.pas.0000170348.40057.60","article-title":"Endocrine mucin-producing sweat gland carcinoma: Twelve new cases suggest that it is a precursor of some invasive mucinous carcinomas","volume":"29","author":"Zembowicz","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"R3-38-20240829","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/DAD.0b013e31826367be","article-title":"Endocrine mucin-producing sweat gland carcinoma: Report of two cases of an under-recognized malignant neoplasm and review of the literature","volume":"35","author":"Dhaliwal","year":"2013","journal-title":"Am J Dermatopathol"},{"key":"R4-38-20240829","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1097\/00000478-199712000-00014","article-title":"Endocrine mucin-producing sweat gland carcinoma: A cutaneous neoplasm analogous to solid papillary carcinoma of breast","volume":"21","author":"Flieder","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"R5-38-20240829","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.ajo.2012.09.030","article-title":"Mucin-producing sweat gland carcinoma of the eyelid: Diagnostic and prognostic considerations","volume":"155","author":"Hoguet","year":"2013","journal-title":"Am J Ophthalmol"},{"key":"R6-38-20240829","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1097\/DSS.0000000000001138","article-title":"Endocrine mucin-producing sweat gland carcinoma treated with mohs micrographic surgery","volume":"43","author":"Scott","year":"2017","journal-title":"Dermatol Surg"},{"key":"R7-38-20240829","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s10792-015-0127-x","article-title":"Endocrine mucin-producing sweat gland carcinoma of the eyelid","volume":"35","author":"Collinson","year":"2015","journal-title":"Int Ophthalmol"},{"key":"R8-38-20240829","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/DAD.0000000000000116","article-title":"Primary cutaneous endocrine mucin-producing sweat gland carcinoma co-occurring simultaneously with low-grade ductal mucinous breast cancer: A clinicopathologic conundrum","volume":"37","author":"Jedrych","year":"2015","journal-title":"Am J Dermatopathol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_342_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:34:19Z","timestamp":1787067259000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_342_19"}},"subtitle":["A rare case report"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_342_19","relation":{},"ISSN":["0377-4929"],"issn-type":[{"value":"0377-4929","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}