{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:34:08Z","timestamp":1787841248401,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Fungal endocarditis is a rare infection of the heart valve, forming less than 3% of infective endocarditis. Prosthetic valves have a higher rate of infection in the initial three months of surgery. Among the prosthetic valve endocarditis, fungal etiology comprises about 4% of all infections. This devastating infection carries a mortality rate of up to 62.5%. The most common causative fungal organism is\n                    <jats:italic toggle=\"yes\">Candida<\/jats:italic>\n                    spp, which invariably is a consequence of horizontal transmission. Embolic phenomena form the most frequent type of clinical presentation of underlying fungal prosthetic valve endocarditis. We report here the autopsy findings of a 51-year-male, with a recent prosthetic bi-leaflet mitral valve replacement, who presented with extensive intracranial hemorrhage.\n                  <\/jats:p>","DOI":"10.4103\/ijpm.ijpm_343_24","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:00:34Z","timestamp":1774936834000},"page":"180-183","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Fungal prosthetic endocarditis presenting as intracranial hemorrhage"],"prefix":"10.4103","volume":"69","author":[{"given":"Tapamita","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Pathology, Command Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnendu","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Command Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran","family":"Bhagwat","sequence":"additional","affiliation":[{"name":"Department of Neurology, Command Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj Gopal","family":"Madakshira","sequence":"additional","affiliation":[{"name":"Department of Pathology, Command Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,8,8]]},"reference":[{"key":"R1-20260403","doi-asserted-by":"crossref","first-page":"e0001923","DOI":"10.1128\/cmr.00019-23","article-title":"Fungal endocarditis: Pathophysiology, epidemiology, clinical presentation, diagnosis, and management","volume":"36","author":"Thompson","year":"2023","journal-title":"Clin Microbiol Rev"},{"key":"R2-20260403","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1161\/01.CIR.72.1.31","article-title":"Risk factors for the development of prosthetic valve endocarditis","volume":"72","author":"Calderwood","year":"1985","journal-title":"Circulation"},{"key":"R3-20260403","doi-asserted-by":"crossref","first-page":"860","DOI":"10.5005\/jp-journals-10071-23915","article-title":"Clinical profile of prosthetic valve endocarditis due to candida parapsilosis: An 11-year retrospective observational study from a quaternary cardiac referral institute in India","volume":"25","author":"Ponnambath","year":"2021","journal-title":"Indian J Crit Care Med"},{"key":"R4-20260403","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev-micro-091014-104330","article-title":"Candida albicans biofilms and human disease","volume":"69","author":"Nobile","year":"2015","journal-title":"Annu Rev Microbiol"},{"key":"R5-20260403","doi-asserted-by":"crossref","first-page":"acmi000462","DOI":"10.1099\/acmi.0.000462.v4","article-title":"Prosthetic valve endocarditis due to Candida parapsilosis - A rare case report","volume":"5","author":"Sharma","year":"2023","journal-title":"Access Microbiol"},{"key":"R6-20260403","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.echo.2017.03.007","article-title":"Diagnostic accuracy of transthoracic echocardiography for infective endocarditis findings using transesophageal echocardiography as the reference standard: A meta-analysis","volume":"30","author":"Bai","year":"2017","journal-title":"J Am Soc Echocardiogr"},{"key":"R7-20260403","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/civ933","article-title":"Clinical practice guideline for the management of candidiasis:2016 Update by the infectious diseases society of America","volume":"62","author":"Pappas","year":"2016","journal-title":"Clin Infect Dis"},{"key":"R8-20260403","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/myc.13398","article-title":"Clinical features, diagnosis and treatment outcome of fungal endocarditis: A systematic review of reported cases","volume":"65","author":"Meena","year":"2022","journal-title":"Mycoses"},{"key":"R9-20260403","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.21037\/atm-20-3880","article-title":"A narrative review of early surgery versus conventional treatment for infective endocarditis: Do we have an answer?","volume":"8","author":"Benedetto","year":"2020","journal-title":"Ann Transl Med"},{"key":"R10-20260403","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/j.1439-0507.2010.01884.x","article-title":"Fungal prosthetic valve endocarditis: Mayo Clinic experience with a clinicopathological analysis","volume":"54","author":"Boland","year":"2011","journal-title":"Mycoses"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_343_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:47:27Z","timestamp":1787838447000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_343_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,8]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_343_24","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,8]]},"assertion":[{"value":"2024-04-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-10","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}