{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:49:02Z","timestamp":1787071742514,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Though thymomas are the commonest neoplasms of the anterior mediastinum, metaplastic thymoma is an extremely rare subtype, with only a few reported cases. It was included in the 2004 WHO classification of thymic epithelial tumors and exhibits a biphasic morphology distinct from the conventional thymomas. It has a benign clinical course with extremely rare cases showing recurrence and malignant transformation. However, metaplastic thymoma needs to be histologically distinguished from other more aggressive mediastinal neoplasms displaying biphasic patterns. Here we report a case of an incidentally detected large mediastinal mass with features of metaplastic thymoma.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_348_24","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T17:00:09Z","timestamp":1755536409000},"page":"886-888","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Metaplastic thymoma: A rare and indolent subtype"],"prefix":"10.4103","volume":"68","author":[{"given":"Megha Harekrishna","family":"Kasture","sequence":"first","affiliation":[{"name":"Department of Histopathology, Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandralekha Shyamsunder","family":"Tampi","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"R1-20251208","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1309\/AJCP0T1JFYLMPHMI","article-title":"Metaplastic thymoma of the mediastinum. A clinicopathologic, immunohistochemical, and genetic analysis","volume":"137","author":"Liu","year":"2012","journal-title":"Am J of Clinic Pathol"},{"key":"R4-20251208","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/s41379-019-0382-x","article-title":"Metaplastic thymoma: A distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions","volume":"33","author":"Vivero","year":"2020","journal-title":"Mod Pathol"},{"key":"R5-20251208","first-page":"463","article-title":"Giant multilocular-cystic metaplastic thymoma: A case report","volume":"16","author":"Han","year":"2023","journal-title":"Pharmgenomics Pers Med"},{"key":"R6-20251208","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1097\/00000478-199711000-00006","article-title":"Thymoma with pseudosarcomatous stroma: Report of an unusual histologic variant of thymic epithelial neoplasm that may simulate carcinosarcoma","volume":"21","author":"Suster","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"R7-20251208","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0344-0338(99)80005-3","article-title":"Low-grade metaplastic carcinomas of the thymus: biphasic thymic epithelial tumors with mesenchymal metaplasia--an update","volume":"195","author":"Yoneda","year":"1999","journal-title":"Pathol Res Pract"},{"key":"R8-20251208","first-page":"30","article-title":"Metaplastic thymoma \u2013a rare case report","volume":"17","author":"Hemalatha","year":"2018","journal-title":"IOSR J Dent Med Sci (IOSR-JDMS)"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_348_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:53:07Z","timestamp":1787068387000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_348_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_348_24","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,14]]},"assertion":[{"value":"2024-05-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}