{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:34:08Z","timestamp":1787841248396,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Disorders of sexual development (DSD) comprise a group of congenital conditions, occurring in approximately 1 in 4,500 to 5,500 newborns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Over a 3-year period, seven cases presented with ambiguous genitalia, primary amenorrhea, and abdominal masses and were admitted to our hospital\u2019s General Surgery and Gynaecology wards. Radiological, cytogenetics, and hormonal evaluation was done, followed by surgical excision and histopathological examination of the gonads. The study was conducted with proper written informed consent from parents and received approval from the Institutional Ethics Committee.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Out of four cases diagnosed with mixed gonadal dysgenesis (MGD), one had dysgerminoma, one had both dysgerminoma and gonadoblastoma, and another had bilateral gonadoblastoma. Three other cases were diagnosed as ovo-testicular DSD. We experienced varied presentations of dysgenetic gonads in DSD \u2013 ovotestis to streak gonad and dysgenetic testis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Early diagnosis and categorization of disorders of sex development (DSD) are crucial to prevent adverse outcomes and ensure optimal management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpm.ijpm_375_25","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T13:00:18Z","timestamp":1768827618000},"page":"64-69","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Spectrum of gonadal morphology in disorders of sexual development: A case series"],"prefix":"10.4103","volume":"69","author":[{"given":"PM","family":"Abida","sequence":"first","affiliation":[{"name":"Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bandyopadhyay","family":"Arghya","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mondal","family":"Ambalika","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moumita","family":"Maiti","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barui","family":"Gopinath","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"R1-20260403","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.beem.2007.11.001","article-title":"Disorders of sex development:A new definition and classification","volume":"22","author":"Hughes","year":"2008","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"R2-20260403","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000499274","article-title":"Disorders of sexual development:Current status and progress in the diagnostic approach","volume":"13","author":"Garc\u00eda-Acero","year":"2020","journal-title":"Curr Urol"},{"key":"R3-20260403","doi-asserted-by":"crossref","first-page":"e488","DOI":"10.1542\/peds.2006-0738","article-title":"Consensus statement on management of intersex disorders international consensus conference on 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Health"},{"key":"R7-20260403","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.urology.2011.02.036","article-title":"Ovotesticular disorder of sex development with mosaic 45, X\/46, X, idic(Y) (q11.23) karyotype and streak gonad","volume":"78","author":"Tran","year":"2011","journal-title":"Urology"},{"key":"R8-20260403","doi-asserted-by":"crossref","first-page":"171","DOI":"10.4103\/GMIT.GMIT_107_19","article-title":"46\u00d7Y ovotesticular disorder:A rare case report with review of literature","volume":"10","author":"Meenal","year":"2021","journal-title":"Gynecol Minim Invasive Ther"},{"key":"R9-20260403","doi-asserted-by":"crossref","first-page":"e408","DOI":"10.6061\/clinics\/2019\/e408","article-title":"Germ cell tumors in dysgenetic gonads","volume":"74","author":"Piazza","year":"2019","journal-title":"Clin Sao Paulo Braz"},{"key":"R10-20260403","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.bpobgyn.2017.11.005","article-title":"Disorders of sex development","volume":"48","author":"Witchel","year":"2018","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"R11-20260403","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.18203\/2320-6012.ijrms20202283","article-title":"Histopathological spectrum of disorders of sexual development:A case series of seven cases","volume":"8","author":"Bolde","year":"2020","journal-title":"Int J Res Med Sci"},{"key":"R13-20260403","doi-asserted-by":"crossref","first-page":"644","DOI":"10.20945\/2359-3997000000091","article-title":"Early development of a gonadal tumor in a patient with mixed gonadal dysgenesis","volume":"62","author":"Cunha","year":"2018","journal-title":"Arch Endocrinol Metab"},{"key":"R14-20260403","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1097\/JU.0000000000004137","article-title":"Mixed gonadal dysgenesis:A narrative literature review and clinical primer for the urologist","volume":"212","author":"Corona","year":"2024","journal-title":"J Urolog"}],"container-title":["Indian Journal of Pathology and 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