{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T17:32:29Z","timestamp":1788802349770,"version":"build-2803163510"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>IgG4-RD is an immune-mediated systemic fibroinflammatory condition with characteristic clinicopathological findings. The exact etiology is uncertain. A combination of environmental and genetic factors is considered to be involved. It can affect multiple organs often mimicking malignancy or infectious disorder. Because of myriad of clinical presentations, the clinical diagnosis is cumbersome and requires a detailed histopathological, radiological, and serological workup. IgG4-retroperitoneal fibrosis is usually seen as a component of systemic manifestation of the disease that presents as mass lesion causing pressure and pain symptoms. These clinical symptoms are usually of insidious onset with gradually progressive course. The early diagnosis and treatment is essential to prevent its long-term irreversible complications. Isolated retroperitoneal fibrosis due to IgG4-RD is rare, as is being reported in our elderly male patient. Our case report highlights the rare presentation of IgG4-related RPF mimicking renal cell carcinoma.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_568_24","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T12:00:43Z","timestamp":1741867243000},"page":"799-802","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Rare case of IgG4-related retroperitoneal fibrosis mimicking renal cell carcinoma: A diagnostic challenge"],"prefix":"10.4103","volume":"68","author":[{"given":"Blessy","family":"Mathew","sequence":"first","affiliation":[{"name":"Department of Pathology, Command Hospital, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devika","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Pathology, Command Hospital, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav Pratap Singh","family":"Gahlot","sequence":"additional","affiliation":[{"name":"Department of Pathology, Command Hospital, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puneet","family":"Takkar","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Command Hospital, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"R1-20251208","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/s41584-020-0500-7","article-title":"IgG 4-related disease: An update on pathophysiology and implications for clinical care","volume":"16","author":"Perugino","year":"2020","journal-title":"Nat Rev Rheumatol"},{"key":"R2-20251208","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/s41577-023-00871-z","article-title":"The unique properties of IgG4 and its roles in health and disease","volume":"23","author":"Rispens","year":"2023","journal-title":"Nat Rev Immunol"},{"key":"R3-20251208","doi-asserted-by":"crossref","first-page":"rka.e020","DOI":"10.1093\/rap\/rkae020","article-title":"Current and future advances in practice: IgG4-related disease","volume":"8","author":"Wallace","year":"2024","journal-title":"Rheumatol Adv Pract"},{"key":"R4-20251208","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.jaci.2014.03.034","article-title":"De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease","volume":"134","author":"Mattoo","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"R5-20251208","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/s13075-018-1718-5","article-title":"Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse","volume":"20","author":"Lanzillotta","year":"2018","journal-title":"Arthritis Res Ther"},{"key":"R6-20251208","first-page":"e13608","article-title":"IgG4-related disease retroperitoneal fibrosis: An unusual cause of low back pain","volume":"13","author":"Bangolo","year":"2021","journal-title":"Cereus"},{"key":"R7-20251208","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2147\/IJNRD.S239160","article-title":"Renal involvement in retroperitoneal fibrosis: prevalence, impact and management challenges","volume":"14","author":"Mizushima","year":"2021","journal-title":"Int J Nephrol Renovasc Dis"},{"key":"R8-20251208","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/rheumatology\/keaa411","article-title":"Clinical features of IgG4-related retroperitoneal fibrosis among 407 patients with IgG4-related disease: A retrospective study","volume":"60","author":"Liu","year":"2021","journal-title":"Rheumatology (Oxford)"},{"key":"R9-20251208","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1097\/PAS.0b013e3181f7266b","article-title":"IgG4-related disease: A cross sectional study of 114 cases","volume":"34","author":"Zen","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"R10-20251208","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.pan.2021.03.001","article-title":"Serum free light chain assessment in type I autoimmune pancreatitis","volume":"2","author":"Ikemune","year":"2021","journal-title":"Pancreatology"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_568_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:53:07Z","timestamp":1787068387000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_568_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,13]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_568_24","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,13]]},"assertion":[{"value":"2024-07-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}