{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:22:04Z","timestamp":1787840524893,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T00:00:00Z","timestamp":1749254400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We reported a case of dedifferentiated ovarian carcinoma in a 51-year-old woman. The microscopic tumor consisted of well-differentiated endometrioid carcinoma and undifferentiated carcinoma. Undifferentiated carcinoma was characterized by high-grade nuclear features, mainly solid growth, vacuolar nuclei, frequent nuclear division, and necrosis. Undifferentiated carcinoma did not express epithelial immune markers; p53 was completely deficient in both components; the expression of MMR proteins was only deficient in low-grade endometrioid carcinoma, while it was preserved in undifferentiated carcinoma; SMARCB1\/INI1 was diffused expression in both components; SOX2 was diffusely expressed in undifferentiated carcinoma, but not in well-differentiated components; SMARCA4\/BRG1 was inactivated in undifferentiated components. These resulted in a poor prognosis.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_58_24","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T05:00:15Z","timestamp":1749445215000},"page":"854-857","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Ovarian-dedifferentiated endometrioid adenocarcinoma: A rare case report"],"prefix":"10.4103","volume":"68","author":[{"given":"Cao","family":"Beibei","sequence":"first","affiliation":[{"name":"Department of Pathology, Zhejiang Hospital, Xihu, Hangzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Junhai","sequence":"additional","affiliation":[{"name":"Department of General Practice, Renmin Hospital of Wuhan University, Wuchang, Wuhan, Hubei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru","family":"Guoqing","sequence":"additional","affiliation":[{"name":"Department of Pathology, Zhejiang Provincial People\u2019s Hospital, Gongshu District, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Zhejiang Hospital, Xihu, Hangzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,7]]},"reference":[{"key":"R1-20251208","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.3390\/diagnostics12123146","article-title":"Pilomatrix-like high-grade endometrioid carcinoma of the ovary: Case report, literature review, and differential diagnosis","volume":"12","author":"Santoro","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"R2-20251208","first-page":"33","article-title":"Dedifferentiated carcinoma of the ovary. 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