{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:22:02Z","timestamp":1787840522751,"version":"build-2784847793"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T00:00:00Z","timestamp":1749254400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>An 18-year-old female presented with obstructive jaundice and significant weight loss for 2 months with acute cholangitis. Examination revealed pallor, icterus, left supraclavicular lymphadenopathy, and hepatosplenomegaly. USG of the neck showed a supraclavicular lymph node of size 6 \u00d7 5 \u00d7 3 cm. MRCP suggested Dilated CBD and IHBRs with an abrupt cut-off at the cut off at the distal end. CECT chest and abdomen showed cervical, mediastinal, and peri-pancreatic lymphadenopathy, which was causing distal CBD obstruction. EUS-guided FNAC from peri-pancreatic lymph nodes was taken, followed by ERCP-guided CBD stenting was done to relieve acute cholangitis. On FNAC, there was a suspicion of non-Hodgkin lymphoma. An excision biopsy from the left supraclavicular lymph node was taken, which revealed ALK-positive Anaplastic Large T-Cell Lymphoma (ALCL). The patient was given appropriate chemotherapy, which showed significant clinical as well as radiological response.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_592_24","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T05:00:13Z","timestamp":1749445213000},"page":"850-853","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Anaplastic large T-cell Lymphoma presenting as obstructive jaundice: Revisiting the pathologist\u2019s role"],"prefix":"10.4103","volume":"68","author":[{"given":"Shrey","family":"Bhatt","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ujjwal","family":"Sonika","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surbhi","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Pathology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alok Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puja","family":"Sakhuja","sequence":"additional","affiliation":[{"name":"Department of Pathology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,7]]},"reference":[{"key":"R1-20251208","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1007\/s10620-007-9786-4","article-title":"Biliary tract obstruction secondary to malignant lymphoma: Experience at a referral center","volume":"52","author":"Odemis","year":"2007","journal-title":"Dig Dis Sci"},{"key":"R2-20251208","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1055\/s-2008-1040582","article-title":"Differential diagnosis of jaundice in lymphoma patients","volume":"7","author":"Birrer","year":"1987","journal-title":"Semin Liver Dis"},{"key":"R3-20251208","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.pedneo.2023.09.004","article-title":"Primary pancreatic lymphoma in a child presenting with rapidly progressive obstructive jaundice","volume":"65","author":"Lojanatorn","year":"2024","journal-title":"Pediatr Neonatol"},{"key":"R4-20251208","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3892\/mco.2022.2548","article-title":"Primary non-Hodgkin lymphoma of the extra-hepatic bile duct: A case report","volume":"17","author":"Pararas","year":"2022","journal-title":"Mol Clin Oncol"},{"key":"R5-20251208","doi-asserted-by":"crossref","first-page":"379","DOI":"10.21037\/jgo.2018.07.13","article-title":"An unusual case of obstructive jaundice: Ampullary Burkitt lymphoma","volume":"10","author":"Pawar","year":"2019","journal-title":"J Gastrointest Oncol"},{"key":"R6-20251208","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1200\/JCO.1987.5.6.969","article-title":"Biliary tract obstruction secondary to cancer: Management guidelines and selected literature review","volume":"5","author":"Lokich","year":"1987","journal-title":"J Clin Oncol"},{"key":"R7-20251208","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1002\/1097-0142(19950401)75:7<1669::AID-CNCR2820750718>3.0.CO;2-3","article-title":"Non-Hodgkin's lymphoma presenting with biliary tract obstruction. 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