{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:30:39Z","timestamp":1786739439702,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Plasmablastic lymphoma (PBL) is a rare aggressive subtype of mature large B cell lymphoma involving almost exclusively the extranodal regions particularly the oral cavity, frequently described in immunocompromised patients. PBL is characterized histologically by diffuse proliferation of large neoplastic cells resembling B immunoblasts or plasmablasts. The diagnosis of PBL can be difficult due to its ambiguous histopathological features mimicking most large cell lymphomas and lacking a distinctive immunophenotypic pattern. They typically lack expression of CD20 and CD79a but may express plasma cell marker, CD138. Aberrant immunoexpression of CD3, a T-cell marker in PBL in the absence of other B-cell markers is exceptionally rare, may potentially lead to incorrect interpretation. Herein, we report a case series of CD3-positive PBL of oral cavity in two individuals, which were initially misdiagnosed as high-grade T-cell lymphomas including extranodal NK\/T-cell lymphoma, nasal type. Useful distinguishing clinical settings, histomorphological features, immunohistochemistry and molecular expression profiles of PBL are discussed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpm.ijpm_616_20","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T10:47:34Z","timestamp":1627555654000},"page":"579-583","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["CD3-positive plasmablastic lymphoma reported in two cases"],"prefix":"10.4103","volume":"64","author":[{"given":"Yin Ping","family":"Wong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noraidah","family":"Masir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mian 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lymphoma","volume":"125","author":"Castillo","year":"2015","journal-title":"Blood"},{"key":"R8-29-20240829","doi-asserted-by":"crossref","first-page":"33487","DOI":"10.18632\/oncotarget.16532","article-title":"Clinical and prognostic significance of aberrant T-cell marker expression in 225 cases of de novo diffuse large B-cell lymphoma and 276 cases of other B-cell lymphomas","volume":"8","author":"Tsuyama","year":"2017","journal-title":"Oncotarget"},{"key":"R9-29-20240829","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1038\/modpathol.2017.177","article-title":"CD3-positive plasmablastic B-cell neoplasms: Adiagnostic pitfall","volume":"31","author":"Pan","year":"2018","journal-title":"Mod Pathol"},{"key":"R10-29-20240829","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/978-3-319-99716-2_4","article-title":"Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS)","volume":"176","author":"Oluwasanjo","year":"2019","journal-title":"Cancer Treat Res"},{"key":"R11-29-20240829","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3389\/fped.2019.00141","article-title":"Extranodal natural killer\/T-cell lymphoma, nasal type: Basic science and clinical progress","volume":"7","author":"Harabuchi","year":"2019","journal-title":"Front Pediatr"},{"key":"R12-29-20240829","doi-asserted-by":"crossref","first-page":"315289","DOI":"10.1155\/2015\/315289","article-title":"Plasmablastic lymphoma: A review of current knowledge and future directions","volume":"2015","author":"Elyamany","year":"2015","journal-title":"Adv Hematol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_616_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:28:59Z","timestamp":1786735739000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_616_20"}},"subtitle":["A potential diagnostic caveat"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_616_20","relation":{},"ISSN":["0377-4929"],"issn-type":[{"value":"0377-4929","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}