{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:37:36Z","timestamp":1786736256318,"version":"build-2736575974"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Pathol Microbiol"],"published-print":{"date-parts":[[2019]]},"DOI":"10.4103\/ijpm.ijpm_703_18","type":"journal-article","created":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T09:19:31Z","timestamp":1567156771000},"page":"399","source":"Crossref","is-referenced-by-count":2,"title":["Duodenal mucosal immune cells in treatment-naive adult patients with celiac disease having different histological grades and controls"],"prefix":"10.4103","volume":"62","author":[{"given":"Prasenjit","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GauravP","family":"S. Gahlot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandana","family":"Baloda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alka","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreenivas","family":"Vishnubhatla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SiddharthaDatta","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GovindK","family":"Makharia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0377-4929.263498-1","first-page":"907","volume-title":"Celiac disease: An immunological jigsaw","author":"Meresse","year":"2012","journal-title":"Immunity"},{"key":"key-10.4103\/0377-4929.263498-2","first-page":"331","volume-title":"Anatomical basis of tolerance and immunity to intestinal antigens","author":"Mowat","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"key-10.4103\/0377-4929.263498-3","first-page":"232","volume-title":"Oral tolerance to food protein","author":"Pabst","year":"2012","journal-title":"Mucosal Immunol"},{"key":"key-10.4103\/0377-4929.263498-4","first-page":"858","volume-title":"Tissue-mediated control of immunopathology in coeliac disease","author":"Jabri","year":"2009","journal-title":"Nat Rev Immunol"},{"key":"key-10.4103\/0377-4929.263498-5","first-page":"5317","volume-title":"Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance","author":"Itoh","year":"1999","journal-title":"J Immunol"},{"key":"key-10.4103\/0377-4929.263498-6","first-page":"351","volume-title":"Regulatory T cells: Development, function and role in autoimmunity","author":"Lan","year":"2005","journal-title":"Autoimmun Rev"},{"key":"key-10.4103\/0377-4929.263498-7","first-page":"330","volume-title":"Foxp3 programs the development and function of CD4+CD25+ regulatory T cells","author":"Fontenot","year":"2003","journal-title":"Nat Immunol"},{"key":"key-10.4103\/0377-4929.263498-8","first-page":"329","volume-title":"Regulatory T cell lineage specification by the fork-head transcription factor Foxp3","author":"Fontenot","year":"2005","journal-title":"Immunity"},{"key":"key-10.4103\/0377-4929.263498-9","first-page":"1209","volume-title":"CD4 Tregs and immune control","author":"Fehervari","year":"2004","journal-title":"J Clin Invest"},{"key":"key-10.4103\/0377-4929.263498-10","first-page":"1783","volume-title":"Cutting edge: Contact-mediated suppression by CD4CD25 regulatory cells involves a granzyme B-dependent, perforin independent mechanism","author":"Gondek","year":"2005","journal-title":"J Immunol"},{"key":"key-10.4103\/0377-4929.263498-11","first-page":"403","volume-title":"Adaptive Treg generation by DCs and their functional analysis","author":"Wang","year":"2010","journal-title":"Methods Mol Biol"},{"key":"key-10.4103\/0377-4929.263498-12","first-page":"56","volume-title":"IPEX and FOXP3: Clinical and research perspectives","author":"Wildin","year":"2005","journal-title":"J Autoimmun"},{"key":"key-10.4103\/0377-4929.263498-13","first-page":"42","volume-title":"Gastrointestinal pathology in celiac disease: A case series of 150 consecutive newly diagnosed patients","author":"Brown","year":"2012","journal-title":"Am J Clin Pathol"},{"key":"key-10.4103\/0377-4929.263498-14","first-page":"2819","volume-title":"Healthy HLA-DQ2.5+ subjects lack regulatory and memory T cells specific for immunodominant gluten epitopes of celiac disease","author":"Christophersen","year":"2016","journal-title":"J Immunol"},{"key":"key-10.4103\/0377-4929.263498-15","first-page":"172","volume-title":"Decreased circulating iNKT cell numbers in refractory coeliac disease","author":"Bernardo","year":"2008","journal-title":"Clin Immunol"},{"key":"key-10.4103\/0377-4929.263498-16","doi-asserted-by":"crossref","unstructured":"Cook L, Munier CML, Seddiki N, van Bockel D, Ontiveros N, Hardy MY, et al. Circulating gluten-specific FOXP3+CD39+ regulatory T cells have impaired suppressive function in patients with celiac disease. J Allergy Clin Immunol 2017;140:1592-603.e8.","DOI":"10.1016\/j.jaci.2017.02.015"},{"key":"key-10.4103\/0377-4929.263498-17","first-page":"1513","volume-title":"Regulatory T-cell function is impaired in celiac disease","author":"Granzotto","year":"2009","journal-title":"Dig Dis Sci"},{"key":"key-10.4103\/0377-4929.263498-18","first-page":"422","volume-title":"Increased FoxP3 expression in small-bowel mucosa of children with coeliac disease and type I diabetes mellitus","author":"Vorobjova","year":"2009","journal-title":"Scand J Gastroenterol"},{"key":"key-10.4103\/0377-4929.263498-19","first-page":"604","volume-title":"Impaired control of effector T cells by regulatory T cells: A clue to loss of oral tolerance and autoimmunity in celiac disease?","author":"Hmida","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"key-10.4103\/0377-4929.263498-20","first-page":"430","volume-title":"Increased CD4+CD25+Foxp3+ T cells in peripheral blood of celiac disease patients: Correlation with dietary treatment","author":"Frisullo","year":"2009","journal-title":"Hum Immunol"},{"key":"key-10.4103\/0377-4929.263498-21","first-page":"328","volume-title":"FoxP3 expression in duodenal mucosa in pediatric patients with celiac disease","author":"Brazowski","year":"2010","journal-title":"Pathobiology"},{"key":"key-10.4103\/0377-4929.263498-22","first-page":"498","volume-title":"Infiltration of forkhead box P3-expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes","author":"Tiittanen","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"key-10.4103\/0377-4929.263498-23","first-page":"1185","volume-title":"The histopathology of coeliac disease: Time for a standardized report scheme for pathologists","author":"Oberhuber","year":"1999","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"key-10.4103\/0377-4929.263498-24","first-page":"667","volume-title":"Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease","author":"Forsberg","year":"2002","journal-title":"Gastroenterology"},{"key":"key-10.4103\/0377-4929.263498-25","first-page":"e21281","volume-title":"Potential celiac disease: A model of celiac disease pathogenesis","author":"Sperandeo","year":"2011","journal-title":"PLoS One"},{"key":"key-10.4103\/0377-4929.263498-26","first-page":"5131","volume-title":"Exposure to IL-15 and IL-21 enables autoreactive CD8 T cells to respond to weak antigens and cause disease in a mouse model of autoimmune diabetes","author":"Ramanathan","year":"2011","journal-title":"J Immunol"},{"key":"key-10.4103\/0377-4929.263498-27","first-page":"e1002670","volume-title":"Age dependent TLR3 expression in intestinal epithelium contributes to rotavirus susceptibility","author":"Pott","year":"2012","journal-title":"PloD Pathog"},{"key":"key-10.4103\/0377-4929.263498-28","first-page":"e30642","volume-title":"Activation and inhibition of transglutaminase 2 in mice","author":"Dafik","year":"2012","journal-title":"PLoS One"},{"key":"key-10.4103\/0377-4929.263498-29","first-page":"594","volume-title":"HLA-DQ2.2 restricted gluten reactive T cells produce IL-21 but not IL-17 or IL-22","author":"Bodd","year":"2010","journal-title":"Mucosal Immunol"},{"key":"key-10.4103\/0377-4929.263498-30","first-page":"357","volume-title":"Coordinate induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease","author":"Meresse","year":"2004","journal-title":"Immunity"},{"key":"key-10.4103\/0377-4929.263498-31","doi-asserted-by":"crossref","unstructured":"Meresse B, Cerf-Bensussan N. Innate T cell responses in human gut. Semin Immunol 2009;21;121-9.","DOI":"10.1016\/j.smim.2009.01.002"},{"key":"key-10.4103\/0377-4929.263498-32","first-page":"468","volume-title":"Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity and survival in celiac disease","author":"Di","year":"2006","journal-title":"Gut"},{"key":"key-10.4103\/0377-4929.263498-33","first-page":"1351","volume-title":"Evidence that intestinal intraepithelial lymphocytes are activated cytotoxic T cells in celiac disease but not in giardiasis","author":"Oberhuber","year":"1996","journal-title":"Am J Pathol"},{"key":"key-10.4103\/0377-4929.263498-34","first-page":"51","volume-title":"Changing jejunal \u03b3\u03b4 T cell receptor (TCR)-bearing intraepithelial lymphocyte density in coeliac disease","author":"Iltanen","year":"1999","journal-title":"Clin Exp Immunol"},{"key":"key-10.4103\/0377-4929.263498-35","first-page":"255","volume-title":"Infectious tolerance: Human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells","author":"Jonuleit","year":"2002","journal-title":"J Exp Med"},{"key":"key-10.4103\/0377-4929.263498-36","first-page":"354","volume-title":"Expansion of regulatory CD8+CD25+ T cells after neonatal alloimmunization","author":"Adams","year":"2011","journal-title":"Clin Exp Immunol"},{"key":"key-10.4103\/0377-4929.263498-37","first-page":"801","volume-title":"Dysfunctional CD4+, CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells","author":"Yan","year":"2008","journal-title":"Arthritis Rheum"},{"key":"key-10.4103\/0377-4929.263498-38","first-page":"477","volume-title":"Evaluation of CD4+T-cells and CD8+T-cells in triple-negative invasive breast cancer","author":"Jagtap","year":"2018","journal-title":"Indian J Pathol Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0377-4929","issn-type":"print"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:39:32Z","timestamp":1786732772000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_703_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019]]}},"alternative-id":["263498"],"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_703_18","relation":{},"ISSN":["0377-4929"],"issn-type":[{"value":"0377-4929","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}