{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:18:39Z","timestamp":1787771919161,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Syringoid eccrine carcinoma of nipple is an extremely rare neoplasm of adnexal origin with variable clinical appearance and diverse histologic findings. Syringoid eccrine carcinoma (SEC) is often a diagnostic dilemma due to its morphology and presentation. Usually, these malignancies arise as non-ulcerated nodules or plaques in the head &amp; neck region including the trunk. They are locally aggressive and have an infiltrative growth pattern with a propensity for metastasis. SEC is characterized by syringoma-like tadpole morphology with ductular differentiation and predominant desmoplasia. Immunostaining in SEC is variable and this variability is believed to arise from the tumor\u2019s ability to differentiate along multiple routes including sweat secretory and or ductal differentiation. Here we present a rare case of SEC\/ syringomatous carcinoma of nipple in a 51-year-old male breast with associated axillary lymph node metastasis. As per English literature, this is the second case of SEC in nipple of male patient.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_716_23","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T06:01:01Z","timestamp":1708495261000},"page":"401-404","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report"],"prefix":"10.4103","volume":"67","author":[{"given":"Mukund","family":"Sable","sequence":"first","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nibedita","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinamyee","family":"Panigrahi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pritinanda","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Surgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1001\/archderm.1969.01610260110021","article-title":"Basal cell tumor with eccrine differentiation (eccrine epithelioma)","volume":"100","author":"Freeman","year":"1969","journal-title":"Arch Dermatol"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1111\/j.1365-4632.2006.02664.x","article-title":"Syringoid eccrine carcinoma with apparently aggressive transformation:Case report and review of the literature","volume":"45","author":"Nishizawa","journal-title":"Int J Dermatol"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1097\/00000478-198307080-00003","article-title":"Syringomatous adenoma of the nipple","volume":"7","author":"Rosen","year":"1983","journal-title":"Am J Surg Pathol"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1075-122X.2004.21518.x","article-title":"Infiltrating syringomatous adenoma of the nipple:A case report and 20-year retrospective review","volume":"10","author":"Carter","year":"2004","journal-title":"Breast J"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000338370","article-title":"A case of syringomatous adenoma of the nipple","volume":"4","author":"Ichinokawa","year":"2012","journal-title":"Case Rep Dermatol"},{"key":"R6-20240829","first-page":"45","article-title":"Metastatic syringoid eccrine carcinoma of the nipple","volume":"5","author":"Ballardini","year":"2012","journal-title":"Int Med Case Rep J"},{"key":"R8-20240829","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1136\/jclinpath-2011-200069","article-title":"Syringoid eccrine carcinoma:A clinicopathological and immunohistochemical study of four cases","volume":"64","author":"Sidiropoulos","year":"2011","journal-title":"J Clin Pathol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_716_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:20:47Z","timestamp":1787768447000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_716_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,19]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_716_23","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,19]]},"assertion":[{"value":"2023-08-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}