{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:25:03Z","timestamp":1787757903381,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The presence of mucin is a rare feature in thyroid lesions. It has been documented in a few cases of follicular neoplasms, medullary carcinoma, papillary carcinoma, poorly differentiated carcinoma, mucoepidermoid carcinoma of the thyroid, and metastasis. A 65-year-old woman presented with complaints of anterior neck swelling. The cytological features were Bethesda category III. The right thyroidectomy showed an oncocytic tumor along with luminal and intracytoplasmic mucin. Alcian blue with periodic acid Schiff stain highlighted the acidic nature of the mucin. It was an encapsulated angioinvasive tumor. On immunohistochemistry, tumor cells were positive for thyroglobulin. We report the fourth case of mucin-producing oncocytic thyroid carcinoma with its associated uncommon features, like dominant intracellular mucin, and encapsulated angioinvasion, with a literature review. Since there are only a few case reports on this topic, future studies are warranted to understand its histogenesis, tumor biology, and progression.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_81_25","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T08:00:10Z","timestamp":1780560010000},"page":"348-350","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Mucin-producing oncocytic thyroid carcinoma\u2014A rare report with literature review"],"prefix":"10.4103","volume":"69","author":[{"given":"Sushmita","family":"Vangapandu","sequence":"first","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvendu","family":"Purkait","sequence":"additional","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit K.","family":"Adhya","sequence":"additional","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh K.","family":"Swain","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavithra","family":"Ayyanar","sequence":"additional","affiliation":[{"name":"Department of Pathology and Lab Medicine, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"R1-20260707","doi-asserted-by":"crossref","first-page":"155","DOI":"10.4137\/CCRep.S10520","article-title":"Follicular adenoma with extensive extracellular mucin deposition: Report on two cases","volume":"5","author":"Kim","year":"2012","journal-title":"Clin Med Insights Case Rep"},{"key":"R2-20260707","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1080\/00313020600561963","article-title":"Mucinous variant of follicular carcinoma of the thyroid gland","volume":"38","author":"Cretney","year":"2006","journal-title":"Pathology"},{"key":"R3-20260707","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1177\/1066896915617026","article-title":"Mucinous variant of follicular carcinoma of the thyroid gland: Case report and review of the literature","volume":"24","author":"Squillaci","year":"2016","journal-title":"Int J Surg Pathol"},{"key":"R4-20260707","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1159\/000333228","article-title":"Fine-needle aspiration of mucin-producing thyroid tumors","volume":"55","author":"Yang","year":"2011","journal-title":"Acta Cytol"},{"key":"R5-20260707","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.5858\/2000-124-1547-MMSAOC","article-title":"Mixed mucus-secreting and oncocytic carcinoma of the thyroid: Pathologic, histochemical, immunohistochemical, and ultrastructural study of a case","volume":"124","author":"Uccella","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"R6-20260707","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1046\/j.1365-2559.200-.01561.x","article-title":"Oncocytic thyroid carcinoma with extensive myxoid stroma","volume":"42","author":"Kuma","year":"2003","journal-title":"Histopathology"},{"key":"R7-20260707","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1365-2303.2009.00704.x","article-title":"Hurthle cell carcinoma with myxoid stroma - A rare entity and a diagnosis pitfall","volume":"21","author":"Li","year":"2010","journal-title":"Cytopathology"},{"key":"R8-20260707","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/path.1711590208","article-title":"The ultimobranchial gland and congenital thyroid abnormalities in man","volume":"159","author":"Williams","year":"1989","journal-title":"J Pathol"},{"key":"R9-20260707","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13044-019-0062-4","article-title":"Mucin in benign thyroid nodules: Treatment related change or not?","volume":"12","author":"Handra-Luca","year":"2019","journal-title":"Thyroid Res"},{"key":"R10-20260707","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1186\/s12885-020-06915-0","article-title":"Clinical characteristics and prognostic factors of Hurthle cell carcinoma: A population based study","volume":"20","author":"Zhou","year":"2020","journal-title":"BMC Cancer"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_81_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:58:48Z","timestamp":1787756328000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_81_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_81_25","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-01-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}