{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:30:25Z","timestamp":1786728625496,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T00:00:00Z","timestamp":1738886400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Massive ovarian oedema, though rare, frequently mimics an ovarian neoplasm, both clinically and radiologically. Here, we discuss the case of a 12-year-old girl who presented with intermittent pain in the lower abdomen for last one month associated with vomiting. A suspicion of germ cell neoplasm was raised on ultrasound despite mildly raised serum markers. Microscopy from left salpingo-ophrectomy specimen revealed marked oedema of ovarian stroma with preserved primordial follicles at the periphery only. This case highlights the importance of a high index of suspicion, clinically, radiologically and pathologically, especially in cases with only mildly raised serum markers to avoid unwarranted surgery and preserve hormonal function as well as fertility in some cases.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_83_24","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T08:02:19Z","timestamp":1738915339000},"page":"450-451","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Massive edema of ovary masquerading as neoplasm in a preteen girl"],"prefix":"10.4103","volume":"68","author":[{"given":"Ruchi","family":"Rathore","sequence":"first","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surabhi","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Kumari","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Mathur","sequence":"additional","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,7]]},"reference":[{"key":"R1-20250721","first-page":"564","article-title":"Massive edema of the ovary simulating fibroma","volume":"34","author":"Kalstone","year":"1969","journal-title":"Obstet Gynecol"},{"key":"R2-20250721","doi-asserted-by":"crossref","first-page":"172","DOI":"10.4103\/2249-4863.184658","article-title":"Massive ovarian edema: A case report presenting as a diagnostic dilemma","volume":"5","author":"Varma","year":"2016","journal-title":"J Family Med Prim Care"},{"key":"R3-20250721","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s13000-016-0469-3","article-title":"Massive ovarian oedema: A misleading clinical entity","volume":"11","author":"Machairiotis","year":"2016","journal-title":"Diagn Pathol"},{"key":"R4-20250721","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3941\/jrcr.v16i4.4408","article-title":"Massive ovarian edema mimicking an ovarian neoplasm in a patient with IVC web","volume":"16","author":"Sehgal","year":"2022","journal-title":"J Radiol Case Rep"},{"key":"R5-20250721","doi-asserted-by":"crossref","first-page":"256","DOI":"10.4103\/jiaps.JIAPS_111_19","article-title":"Massive ovarian edema: An extremely rare cause of ovarian mass in a 7-year-old girl","volume":"25","author":"Mahajan","year":"2020","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"R6-20250721","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/PGP.0b013e31829d76ee","article-title":"Massive ovarian edema associated with a broad ligament leiomyoma: A case report and review","volume":"33","author":"Harrison","year":"2014","journal-title":"Int J Gynecol Pathol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_83_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:29:32Z","timestamp":1786724972000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_83_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,7]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_83_24","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,7]]},"assertion":[{"value":"2024-01-31","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}