{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:31:08Z","timestamp":1790087468595,"version":"4.0.1"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Plasmacytoid urothelial carcinoma (PUC) is a newly recognized rare variant of urothelial carcinoma, which is now being increasingly diagnosed prospectively as well as by retrospective analysis of cases with a poor prognosis. Morphologically, these tumors simulate plasma cell neoplasms and pose a diagnostic challenge. Identifying this variant is essential in two aspects: therapy and prognosis. Here, we present a case who underwent multiple transurethral resection of bladder tumor (TURBT) procedures, each with a diagnosis of urothelial carcinoma, the plasmacytoid type which was confirmed on radical cystectomy, and after 1 year, the patient presented with duodenal metastasis. We discuss the morphological aspects of differentiating this tumor from variants of urothelial carcinoma and other tumors with a plasmacytoid appearance. Despite the recognition and aggressive treatment, the patient expires within 2 years of the first diagnosis of bladder carcinoma.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_840_21","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T23:02:43Z","timestamp":1705014163000},"page":"175-177","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Plasmacytoid urothelial carcinoma with duodenal metastasis\u2014A rare tumor with unusual site of metastasis with grim outcome"],"prefix":"10.4103","volume":"67","author":[{"given":"Aparna","family":"Chenniappan","sequence":"first","affiliation":[{"name":"Department of Pathology (Histopathology Section), Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norton S.","family":"Stephen","sequence":"additional","affiliation":[{"name":"Department of Pathology (Histopathology Section), Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bheemanathi H.","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Department of Pathology (Histopathology Section), Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreerag K.","family":"Sreenivasan","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramkumar","family":"Govindarajalou","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,1,27]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1093\/ajcp\/aqx029","article-title":"Plasmacytoid urothelial carcinoma of the urinary bladder","volume":"147","author":"Fox","year":"2017","journal-title":"Am J Clin Pathol"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1471-2407-13-71","article-title":"Plasmacytoid variant of bladder cancer defines patients with a poor prognosis if treated with cystectomy and adjuvant cisplatin-based chemotherapy","volume":"13","author":"Keck","year":"2013","journal-title":"BMC Cancer"},{"key":"R3-20240829","first-page":"601","article-title":"Plasmacytoid urothelial carcinoma of the urinary bladder:A clinical-pathological study and literature review","volume":"5","author":"Wang","year":"2012","journal-title":"Int J Clin Exp Pathol"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1200\/JCO.2018.36.6_suppl.482","article-title":"Plasmacytoid urothelial carcinoma:A clinicopathological study","volume":"36","author":"Haeshemi-Sadraei","year":"2018","journal-title":"J Clin Oncol"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"381","DOI":"10.4103\/0974-7796.184897","article-title":"Plasmacytoid urothelial carcinoma of the bladder with extensive scrotal wall invasion","volume":"8","author":"Wang","year":"2016","journal-title":"Urol Ann"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1097\/PAS.0b013e318186c45e","article-title":"Plasmacytoid urothelial carcinoma:Detailed analysis of morphology with clinicopathological correlation in 17 cases","volume":"33","author":"Nigwekar","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"144","DOI":"10.4103\/0970-1591.78409","article-title":"A rare case of plasmacytoid urothelial carcinoma of the bladder:Diagnostic dilemmas and clinical implications","volume":"27","author":"Rahman","year":"2011","journal-title":"Indian J Urol"},{"key":"R8-20240829","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/5209059","article-title":"Plasmacytoid urothelial carcinoma of the urinary bladder metastatic to the duodenum:A case report- Diagnostic relevance of GATA3 immunohistochemistry","volume":"2017","author":"Brustmann","year":"2017","journal-title":"Case Rep Pathol"},{"key":"R9-20240829","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1016\/j.humpath.2014.02.024","article-title":"Immunohistochemical evaluation of novel and traditional markers associated with urothelial differentiation in a spectrum of variants of urothelial carcinoma of the urinary bladder","volume":"45","author":"Paner","year":"2014","journal-title":"Hum Pathol"},{"key":"R10-20240829","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1309\/617DWB5GNFWXHW4L","article-title":"CD138 (syndecan-1), a plasma cell marker. Immunohistochemical profile in hematopoietic and nonhematopoietic neoplasms","volume":"121","author":"O'Connell","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"R11-20240829","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1177\/1066896916653673","article-title":"Cd138 expression is observed in the urothelial epithelium and in various urothelial cancers, and cannot be evidence for plasmacytoid urothelial carcinoma","volume":"24","author":"Goto","year":"2016","journal-title":"Int J Surg Pathol"},{"key":"R12-20240829","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/715951","article-title":"Plasmacytoid urothelial carcinoma of the bladder metastatic to the stomach:A case report","volume":"2012","author":"Nabbout","year":"2012","journal-title":"Case Rep Urol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_840_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:02:30Z","timestamp":1787763750000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_840_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,27]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_840_21","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,27]]},"assertion":[{"value":"2021-08-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}