{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:32:01Z","timestamp":1787841121202,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Metanephric tumors of kidney comprise a triad of benign tumors, namely metanephric adenoma (MA), fibroma, and adenofibroma, categorized based on the proportion of epithelial and\/or stromal components. A review of published literature revealed only two cases of malignant transformation, both with sarcomatous transformation. We report an unusual case of malignant transformation in MA in a 35-year-old woman. Histopathologic examination of the mass showed areas reminiscent of benign metanephric tumors, which seamlessly merged with regions displaying high-grade carcinomatous\/dedifferentiated features. To the best of our knowledge, this is the first reported case of MA with carcinomatous transformation. We propose expanding the spectrum of metanephric tumors of the kidney to include both carcinomatous and sarcomatous counterparts in future classifications.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_889_23","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:00:36Z","timestamp":1774936836000},"page":"170-173","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["An exceptional case illustrating the malignant transformation of metanephric adenoma"],"prefix":"10.4103","volume":"69","author":[{"given":"Rakhi","family":"Jagdale","sequence":"first","affiliation":[{"name":"Department of Pathology, Consultant Urosurgeon and Uro-Oncosurgeon, Shri Siddhivinayak Ganapathi Cancer Hospital, Miraj, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supriya","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Consultant Pathologist, Apple Hospital and Research Institute Ltd., Apple Saraswati Multispeciality Hospital, Kolhapur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makarand","family":"Kochikar","sequence":"additional","affiliation":[{"name":"Department of Urology, Consultant Urosurgeon and Uro-Oncosurgeon, Shri Siddhivinayak Ganapathi Cancer Hospital, Miraj, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"R1-20260403","doi-asserted-by":"crossref","first-page":"387","DOI":"10.18632\/oncotarget.28192","article-title":"Metanephric adenoma: Molecular study and review of the literature","volume":"17","author":"Zarco","year":"2022","journal-title":"Oncotarget"},{"key":"R3-20260403","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1097\/00000478-200110000-00010","article-title":"Metanephric adenoma, nephrogenic rests, and Wilms'tumor: A histologic and 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cases","volume":"60","author":"Burger","year":"2007","journal-title":"J Clin Pathol"},{"key":"R7-20260403","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2350\/11-03-1007-CR.1","article-title":"A composite renal tumor: Metanephric adenofibroma, Wilms tumor, and renal cell carcinoma: A missing link?","volume":"15","author":"Galluzzo","year":"2012","journal-title":"Pediatr Dev Pathol"},{"key":"R8-20260403","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1097\/PAS.0000000000000377","article-title":"Molecular and immunohistochemical characterization reveals novel BRAF mutations in metanephric adenoma","volume":"39","author":"Udager","year":"2015","journal-title":"Am J Surg Pathol"},{"key":"R9-20260403","doi-asserted-by":"crossref","first-page":"1020456","DOI":"10.3389\/fonc.2022.1020456","article-title":"Atypical metanephric adenoma: Shares similar histopathological features and molecular changes of metanephric adenoma and epithelial-predominant Wilms'tumor","volume":"14","author":"Yin","year":"2022","journal-title":"Front Oncol"},{"key":"R10-20260403","first-page":"101880","article-title":"Metastatic atypical renal tumour with metanephric characteristics treated with Sunitinib","volume":"40","author":"Mohammad","year":"2021","journal-title":"Urol Case Rep"},{"key":"R11-20260403","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1186\/s12885-015-1211-3","article-title":"Adult metanephric adenoma presumed to be all benign?A clinical perspective","volume":"15","author":"Li","year":"2015","journal-title":"BMC Cancer"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_889_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:42:50Z","timestamp":1787838170000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_889_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_889_23","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2023-04-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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