{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:31:29Z","timestamp":1792099889712,"version":"4.4.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Abnormal uterine bleeding (AUB) is one of the most common problems encountered in gynecological practice. Various benign and malignant disorders of the endometrial tissue show vascular changes such as congestion, dilatation, and vessel wall irregularities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate the vascular morphometry of the endometrial tissue in AUB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A descriptive cross-sectional study of the endometrial tissue in patients presented with AUB was undertaken for vascular morphometric analysis. Histopathological processing of the endometrial tissue samples was done as per the standard format, and the slides were evaluated for vascular morphometry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Out of 150 cases of endometrial tissue in patients presented with AUB, 80 cases were reported as proliferative phase, 41 as secretory phase, 15 as disordered proliferative endometrium, 6 as atrophic phase endometrium, and 4 each of endometrial hyperplasia without atypia and endometrial carcinoma. An average number of endometrial blood vessels and large-sized blood vessels were more in endometrial carcinoma and endometrial hyperplasia without atypia as compared to proliferative phase, secretory phase, atrophic endometrium, and disordered proliferative endometrium. Vessel shape irregularities and vascular congestion were observed in all the cases of atrophic endometrium, endometrial carcinoma, and endometrial hyperplasia without atypia. Endometrial carcinoma showed severe dilatation of the endometrial blood vessels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Vascular morphometry changes were noted in endometrial hyperplasia, endometrial carcinoma, disordered proliferative endometrium, and atrophic phase endometrium. These findings suggest that studies or trials related to anti-angiogenic therapy may help to plan anti-angiogenic therapy in patients with AUB.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpm.ijpm_89_21","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T06:15:36Z","timestamp":1654150536000},"page":"844-850","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Endometrial blood vessel morphometry in patients presenting with abnormal uterine bleeding"],"prefix":"10.4103","volume":"65","author":[{"given":"Neha M.","family":"Bhosale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surekha U.","family":"Arakeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil K.","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhashchandra R.","family":"Mudanur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20240829","doi-asserted-by":"crossref","first-page":"525","DOI":"10.17511\/jopm.2018.i07.08","article-title":"Histomorphological spectrum of endometrial lesion in women presenting with abnormal uterine bleeding: A 3-year study at a tertiary care center","volume":"4","author":"Sharma","year":"2018","journal-title":"Trop J Path Micro"},{"key":"R2-18-20240829","doi-asserted-by":"crossref","first-page":"24629","DOI":"10.18535\/jmscr\/v5i7.56","article-title":"Correlation between histology and bleeding pattern in a case of AUB and risk factors analysis of AUB in reproductive age group","volume":"5","author":"Meena","year":"2017","journal-title":"J Med Sci Clin Res"},{"key":"R3-18-20240829","doi-asserted-by":"crossref","first-page":"503","DOI":"10.18535\/jmscr\/v7i4.86","article-title":"Endometrial pathologies in patients of abnormal uterine bleeding (AUB)","volume":"7","author":"Sinha","year":"2019","journal-title":"J Med Sci Clin Res"},{"key":"R4-18-20240829","first-page":"166","article-title":"Histopathological pattern of endometrium on diagnostic D and C in patients with abnormal uterine bleeding","volume":"17","author":"Khan","year":"2011","journal-title":"Ann King Edw Med Univ"},{"key":"R5-18-20240829","first-page":"216","article-title":"Morphological spectrum of endometrial pathology in middle-aged women with atypical uterine bleeding: A study of 219 cases","volume":"4","author":"Jetley","year":"2013","journal-title":"J Midlife Health"},{"key":"R6-18-20240829","doi-asserted-by":"crossref","first-page":"346","DOI":"10.4103\/0377-4929.42508","article-title":"Morphometric evaluation of endometrial blood vessels","volume":"51","author":"Makhija","year":"2008","journal-title":"Indian J Pathol Microbiol"},{"key":"R7-18-20240829","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1002\/ijc.20930","article-title":"Altered extent, pattern and characteristics of microvascular density are indicators of neoplastic progression in the endometrium","volume":"115","author":"Nayha","year":"2005","journal-title":"Int J Cancer"},{"key":"R8-18-20240829","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.5455\/ijmsph.2017.0511619052017","article-title":"Evaluation of endometrial histopathological patterns in abnormal uterine bleeding: A study of 1545 cases","volume":"6","author":"Chhatrasal","year":"2017","journal-title":"Int J Med Sci Public Health"},{"key":"R9-18-20240829","doi-asserted-by":"crossref","first-page":"24","DOI":"10.18410\/jebmh\/2020\/6","article-title":"Histopathological evaluation of endometrium in cases of abnormal uterine bleeding- An institutional experience in a tertiary care center","volume":"7","author":"Behera","year":"2020","journal-title":"J Evid Based Med Healthc"},{"key":"R10-18-20240829","doi-asserted-by":"crossref","first-page":"3633","DOI":"10.18203\/2320-1770.ijrcog20183767","article-title":"Histopathological spectrum of endometrium in abnormal uterine bleeding","volume":"7","author":"Bindroo","year":"2018","journal-title":"Int J Reprod Contracept Obstet Gynaecol"},{"key":"R11-18-20240829","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3126\/jpn.v2i4.6882","article-title":"Histopathological study of endometrium in abnormal uterine bleeding","volume":"2","author":"Bhatta","year":"2012","journal-title":"J Pathol Nepal"},{"key":"R12-18-20240829","first-page":"490","article-title":"Subramanya. Study of endometrial pathology in abnormal uterine bleeding","volume":"3","author":"Shilpa","year":"2014","journal-title":"Int J Sci Res"},{"key":"R13-18-20240829","doi-asserted-by":"crossref","first-page":"4966","DOI":"10.18203\/2320-1770.ijrcog20175009","article-title":"Endometrial patterns in abnormal uterine bleeding: A retrospective study","volume":"6","author":"Sajeetha","year":"2017","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"R14-18-20240829","first-page":"90","article-title":"Morphometric evaluation of endometrial blood vessels and its clinico-pathological relation in patients with dysfunctional uterine bleeding","volume":"17","author":"Khan","year":"2018","journal-title":"J Dent Med Sci"},{"key":"R15-18-20240829","first-page":"45","article-title":"Clinico pathological evaluation of abnormal uterine bleeding","volume":"2","author":"Mahapatra","year":"2015","journal-title":"J Health Res Rev"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_89_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:57:23Z","timestamp":1787756243000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_89_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_89_21","relation":{},"ISSN":["0377-4929"],"issn-type":[{"value":"0377-4929","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}