{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:35:12Z","timestamp":1787070912576,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T00:00:00Z","timestamp":1720828800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Adrenocortical carcinoma is a rare malignancy and even rarer in infancy. Most of these tumors in the pediatric age group are hormonally active and predominantly present with virilization. We report a case of a 1-year-3-month-old female child presenting with virilization. She presented with hypertension, hypertrichosis, clitoromegaly (virilization), and elevation of plasma testosterone and dehydroepiandrosterone. A discussion of this case and a review of the literature on this entity are presented.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_906_23","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T05:00:36Z","timestamp":1721106036000},"page":"603-605","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Virilizing adrenocortical carcinoma in a female child of Li-Fraumeni syndrome"],"prefix":"10.4103","volume":"68","author":[{"given":"K V Vishnu","family":"Sankar","sequence":"first","affiliation":[{"name":"Department of Urology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debansu","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of Urology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilip Kumar","family":"Pal","sequence":"additional","affiliation":[{"name":"Department of Urology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uttara","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,13]]},"reference":[{"key":"R1-20251031","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0022-5347(05)64023-2","article-title":"Adrenocortical carcinoma:Diagnosis, evaluation and treatment","volume":"169","author":"Ng","year":"2003","journal-title":"J Urol"},{"key":"R2-20251031","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1200\/JCO.2004.08.085","article-title":"Clinical and outcome characteristics of children with adrenocortical tumors:A report from the international pediatric adrenocortical tumor registry","volume":"22","author":"Michalkiewcz","year":"2004","journal-title":"J Clin Oncol"},{"key":"R3-20251031","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nrendo.2010.235","article-title":"Adrenocortical carcinoma:A clinician's update","volume":"7","author":"Fassnacht","year":"2011","journal-title":"Nat Rev Endocrinol"},{"key":"R4-20251031","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1002\/1097-0142(19931201)72:11<3145::AID-CNCR2820721105>3.0.CO;2-N","article-title":"Adrenal cortical carcinoma:Epidemiology and treatment with mitotane and a review of the literature","volume":"72","author":"Wooten","year":"1993","journal-title":"Cancer"},{"key":"R5-20251031","first-page":"32","article-title":"Adrenocortical tumors and hyperplasias in childhood-Etiology, genetics, clinical presentation and therapy","volume":"4","author":"Sutter","year":"2006","journal-title":"Pediatr Endocrinol Rev"},{"key":"R6-20251031","first-page":"251","article-title":"Virilizing adrenocortical carcinoma","volume":"100","author":"Pal","year":"2002","journal-title":"J Indian Med Assoc"},{"key":"R7-20251031","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1590\/S0100-879X2000001000013","article-title":"Adrenocortical tumors in children","volume":"33","author":"Riberio","year":"2000","journal-title":"Braz J Med Biol Res"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_906_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:38:47Z","timestamp":1787067527000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_906_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,13]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_906_23","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,13]]},"assertion":[{"value":"2023-11-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}