{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:35:17Z","timestamp":1787070917075,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T00:00:00Z","timestamp":1726272000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Persistent Mullerian duct syndrome (PMDS) is a rare form of internal male pseudohermaphroditism in phenotypically males with 46 XY karyotype. The syndrome is caused by insufficient amount of Mullerian-inhibiting substance (MIS) or due to insensitivity of the target organ to MIS. Till date, less than 300 cases of PMDS are described in English literature, and the association of testicular tumor is still rarer. We report a case of seminoma of testis with PMDS in a 22-year male who reported with intermittent pain, fullness, and dragging sensation over right-side lower abdomen for 4 years. The radiological impression was testicular mass arising from undescended testis with persistent Mullerian duct structures. Histopathology and immunohistochemistry confirmed the diagnosis. Association of undescended testis increases the likelihood of developing testicular tumor in PMDS. Clinicians and pathologists should be aware of the rare entity while dealing with the cryptorchidism with inguinal hernia, and necessary management should be done to reduce the complications.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_914_23","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T13:15:18Z","timestamp":1726578918000},"page":"630-632","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["An insight into the landscape of a rare tumor-persistent Mullerian duct syndrome with testicular seminoma"],"prefix":"10.4103","volume":"68","author":[{"given":"Nibedita","family":"Sahoo","sequence":"first","affiliation":[{"name":"Department of Pathology, IMS and SUM Medical College and Hospital, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhijna","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Pathology, IMS and SUM Medical College and Hospital, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoranjan","family":"Khuntia","sequence":"additional","affiliation":[{"name":"Department of Radiology, IMS and SUM Medical College and Hospital, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,14]]},"reference":[{"key":"R1-20251031","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1093\/humupd\/dmi014","article-title":"AMH and AMH receptor defects in persistent Mullerian duct syndrome","volume":"11","author":"Josso","year":"2005","journal-title":"Hum Reprod Update"},{"key":"R2-20251031","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000475516","article-title":"The persistent Mullerian duct syndrome:An update based upon a personal experience of 157 cases","volume":"11","author":"Picard","year":"2017","journal-title":"Sex Dev"},{"key":"R3-20251031","first-page":"218","article-title":"Papillary cystadenocarcinoma in a mullerian duct cyst:Report of a case with literature review","volume":"12","author":"Xing","year":"2006","journal-title":"Zhonghua Nan Ke Xue"},{"key":"R4-20251031","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.urology.2005.09.009","article-title":"Giant Mullerian duct cyst with malignant transformation in 15-year-old boy","volume":"67","author":"Warmann","year":"2006","journal-title":"Urology"},{"key":"R5-20251031","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.urolonc.2023.02.008","article-title":"Testicular malignancy in persistent Mullerian duct syndrome:Experience from an apex cancer center with review of literature","volume":"41","author":"Philips","year":"2023","journal-title":"Urol Oncol"},{"key":"R6-20251031","first-page":"231","article-title":"Hernia uteri inguinalis bein manne","volume":"83","author":"Nilson","year":"1939","journal-title":"Acta Chir Scand"},{"key":"R7-20251031","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000475516","article-title":"The persistent m\u00fcllerian duct syndrome:An update based upon a personal experience of 157 cases","volume":"11","author":"Picard","year":"2017","journal-title":"Sex Dev"},{"key":"R8-20251031","first-page":"1","article-title":"Persistent m\u00fcllerian duct syndrome:Understanding the challenges","author":"Chua","year":"2022","journal-title":"Case Rep Urol. 2022"},{"key":"R9-20251031","doi-asserted-by":"crossref","first-page":"407","DOI":"10.4103\/0970-1591.85451","article-title":"Persistent Mullerian duct syndrome with testicular seminoma:A report of two cases","volume":"27","author":"Inuganti","year":"2011","journal-title":"Indian J Urol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_914_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:38:51Z","timestamp":1787067531000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_914_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,14]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_914_23","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,14]]},"assertion":[{"value":"2023-11-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}