{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:33:57Z","timestamp":1787772837320,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Mammary analog secretory carcinoma (MASC) of salivary gland is a recently described entity. Due to its rarity and cytomorphological overlap with other salivary gland tumors, it is often difficult to recognize on cytology. Here we describe three such cases with their histopathological correlation. All the three tumors arose in the parotid gland. They were misdiagnosed as mucoepidermoid carcinoma, acinic cell carcinoma and salivary duct adenocarcinoma, respectively. Final diagnosis of MASC was established on their follow-up histopathology and immunochemistry evaluation. Cytosmears of these tumors showed high cellularity with papillary architecture lying within fluid background rich in foamy macrophages. Nuclear atypia varied from minimal to marked with frequent mitosis and presence of necrosis. Cytoplasmic vacuolation was a consistent finding. Although the cytomorphological features of MASC are not specific, a diagnosis of MASC should be strongly considered in the presence of papillary architecture, prominent cytoplasmic vacuolations of the tumor cells and a background of cyst fluid. Immunohistochemistry on cell block may be done to confirm the diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpm.ijpm_948_20","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T04:19:44Z","timestamp":1717042784000},"page":"783-787","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Cytomorphological features of Mammary Analog secretory carcinoma of parotid gland"],"prefix":"10.4103","volume":"64","author":[{"given":"Shilpy","family":"Jha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swagatika","family":"Samal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavithra","family":"Ayyanar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pritinanda","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvendu","family":"Purkait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukund N.","family":"Sable","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Pradhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit Kumar","family":"Adhya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-29-20240829","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1365-2559.2012.04232.x","article-title":"Clinicopathological characterization of mammary analog secretory carcinoma of salivary glands","volume":"61","author":"Chiosea","year":"2012","journal-title":"Histopathology"},{"key":"R2-29-20240829","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1097\/PAS.0b013e3181d9efcc","article-title":"Mammary analog secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: A hitherto undescribed salivary gland tumor entity","volume":"34","author":"Sk\u00e1lov\u00e1","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"R3-29-20240829","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/dc.23208","article-title":"Aspiration cytology of mammary analog secretory carcinoma of the salivary gland","volume":"43","author":"Jung","year":"2015","journal-title":"Diagn Cytopathol"},{"key":"R4-29-20240829","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/cyt.12810","article-title":"Secretory carcinoma: Fine needle aspiration cytology of a rare parotid gland tumour","volume":"31","author":"Kapatia","year":"2020","journal-title":"Cytopathol"},{"key":"R5-29-20240829","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/dc.21766","article-title":"Mammary analog secretory carcinoma of salivary gland: Cytologic diagnosis and differential diagnosis of an unreported entity","volume":"41","author":"Pisharodi","year":"2013","journal-title":"Diagn Cytopathol"},{"key":"R6-29-20240829","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/cncy.21249","article-title":"The cytological features of mammary analog secretory carcinoma: A series of 6 molecularly confirmed cases","volume":"121","author":"Griffith","year":"2013","journal-title":"Cancer Cytopathol"},{"key":"R7-29-20240829","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/dc.22886","article-title":"Aspiration biopsy of mammary analog secretory carcinoma of accessory parotid gland: Another diagnostic dilemma in matrix-containing tumors of the salivary glands","volume":"42","author":"Levine","year":"2014","journal-title":"Diagn Cytopathol"},{"key":"R8-29-20240829","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/cyt.12465","article-title":"Additional diagnostic features of mammary analog secretory carcinoma on cytology","volume":"29","author":"Gonzalez","year":"2018","journal-title":"Cytopathol"},{"key":"R9-29-20240829","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/cyt.12666","article-title":"Mammary analog secretory carcinoma of salivary gland diagnosed on submandibular gland cytology: A case report and review of the literature","volume":"30","author":"Al-Husseinawi","year":"2019","journal-title":"Cytopathol"},{"key":"R10-29-20240829","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1002\/dc.23139","article-title":"Cytological features of mammary analog secretory carcinoma of salivary gland: Fine-needle aspiration of seven cases","volume":"42","author":"Higuchi","year":"2014","journal-title":"Diagn Cytopathol"},{"key":"R11-29-20240829","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1159\/000477390","article-title":"Difficulty in the cytodiagnosis of mammary analog secretory carcinoma: Survey of 109 cytologists with a case originating from a minor salivary gland","volume":"61","author":"Kai","year":"2017","journal-title":"Acta Cytol"},{"key":"R12-29-20240829","doi-asserted-by":"crossref","first-page":"139","DOI":"10.4103\/ASJO.ASJO_61_16","article-title":"Mammary analog secretory carcinoma parotid gland: Case report of a recently described tumor with review of literature","volume":"3","author":"Gaopande","year":"2017","journal-title":"Asian J Oncol"},{"key":"R13-29-20240829","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/cncy.21245","article-title":"Cytopathologic features of mammary analog secretory carcinoma","volume":"121","author":"Bishop","year":"2013","journal-title":"Cancer Cytopathol"},{"key":"R14-29-20240829","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jasc.2018.02.002","article-title":"The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC): An ASC-IAC-sponsored system for reporting salivary gland fine-needle aspiration","volume":"7","author":"Rossi","year":"2018","journal-title":"J Am Soc Cytopathol"},{"key":"R15-29-20240829","doi-asserted-by":"crossref","first-page":"997","DOI":"10.5858\/arpa.2015-0075-RS","article-title":"Mammary analog secretory carcinoma","volume":"140","author":"Steven","year":"2016","journal-title":"Arch Pathol Lab Med"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_948_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:14:29Z","timestamp":1787771669000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_948_20"}},"subtitle":["Report of 3 cases and review of literature"],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_948_20","relation":{},"ISSN":["0377-4929"],"issn-type":[{"value":"0377-4929","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}