{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:31:13Z","timestamp":1786739473963,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Serum IgG4 is typically measured for Immunoglobulin G4-related Disease (IgG4-RD), a fibroinflammatory condition associated with polyclonal increase in serum IgG4. Yet, increased IgG4 may still be monoclonal, and little is known about IgG4 POEMS syndrome. We present a case of 40-year-old male with a mass lesion in the left sacral ala. The mass was composed of non-neoplastic fibrous tissue and dense infiltrate of mature plasmacytes with dense eosinophilic cytoplasm and eccentrically placed nuclei that express monoclonal Lambda free light chains and show diffuse positivity for IgG and IgG4. We discuss clinical manifestations and challenges encountered in the diagnosis and treatment of this rare coexistence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpm.ijpm_995_20","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T10:47:34Z","timestamp":1627555654000},"page":"584-586","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["IgG4 producing POEMS syndrome"],"prefix":"10.4103","volume":"64","author":[{"given":"Fehmi","family":"Hindilerden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ipek","family":"Yonal-Hindilerden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emine","family":"Gulturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmut","family":"Yuksel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asli Yuksel","family":"Ozturkmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damlanur","family":"Sak\u0131z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-30-20240829","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/ajh.25495","article-title":"POEMS syndrome: 2019 update on diagnosis, risk-stratification, and management","volume":"94","author":"Dispenzieri","year":"2019","journal-title":"Am J Hematol"},{"key":"R2-30-20240829","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3960\/jslrt.54.95","article-title":"IgG4-related disease: Diagnostic methods and therapeutic strategies in Japan","volume":"54","author":"Masaki","year":"2014","journal-title":"J Clin Exp Hematop"},{"key":"R3-30-20240829","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ejrad.2009.06.004","article-title":"18F-FDGPET\/CT in the evaluation of POEMS syndrome","volume":"76","author":"Albert\u00ed","year":"2010","journal-title":"Eur J Radiol"},{"key":"R4-30-20240829","first-page":"588","article-title":"A special subtype of POEMS syndrome: IgG4 subtype","volume":"8","author":"Zheng","year":"2016","journal-title":"Am J Transl Res"},{"key":"R5-30-20240829","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1136\/jcp.2010.082958","article-title":"Multicentric Castleman's disease with abundant IgG4-positive cells: A clinical and pathological analysis of six cases","volume":"63","author":"Sato","year":"2010","journal-title":"J Clin Pathol"},{"key":"R6-30-20240829","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/16078454.2020.1815130","article-title":"IgG4 plasma cell myeloma without clinical evidence of IgG4-related disease: A report of two cases","volume":"25","author":"Gauiran","year":"2020","journal-title":"Hematol"},{"key":"R7-30-20240829","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/pin.12968","article-title":"IgG4 plasma cell myeloma: Clinicopathological characteristics and diagnosis","volume":"70","author":"Ito","year":"2020","journal-title":"Pathol Int"},{"key":"R8-30-20240829","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/bjh.14966","article-title":"Lenalidomide and dexamethasone in patients with POEMS syndrome: Results of aprospective, open-label trial","volume":"179","author":"Nozza","year":"2017","journal-title":"Br J Haematol"},{"key":"R9-30-20240829","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1007\/s00277-010-1133-8","article-title":"Successful treatment with bortezomib and thalidomide for POEMS syndrome","volume":"90","author":"Ohguchi","year":"2011","journal-title":"Ann Hematol"},{"key":"R10-30-20240829","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1136\/jnnp-2012-304874","article-title":"Ambiguous effects of anti-VEGF monoclonal antibody (bevacizumab) for POEMS syndrome","volume":"84","author":"Sekiguchi","year":"2013","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_995_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:29:11Z","timestamp":1786735751000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJPM.IJPM_995_20"}},"subtitle":["A rarely recognized subtype"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_995_20","relation":{},"ISSN":["0377-4929"],"issn-type":[{"value":"0377-4929","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}