{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:19:38Z","timestamp":1787840378644,"version":"build-2784847793"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n This study aimed to determine the relationships between opium use and metabolic syndrome in Fasa PERSIAN cohort data.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n This was an analytical cross-sectional study conducted among participants of the first phase of the Fasa PERSIAN cohort study. A total of 10,074 participants (aged 35\u201370 years) were studied. The MetS was defined as per the National Cholesterol Education Program ATP III (NCEP-ATP III) criteria. Independent sample\n t<\/jats:italic>\n -test and Chi-square test were used for univariate analysis, and multivariate logistic regression was used to control for potential confounders and calculate odds ratios (ORs).\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The MetS prevalence was 24.6% in the whole population (28.42% in women vs. 19.94% in men,\n P<\/jats:italic>\n < 0.001). The prevalence of opium use was 23.2%. The odds of metabolic syndrome in smokers was lower than in non-smokers (OR = 1.17%, 95% CI 1.001\u20131.37).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n The results of this study showed that opium consumption has an inverse relationship with metabolic syndrome. However, this study was cross-sectional, and longitudinal studies are needed for more accurate conclusions. Opium is also a carcinogen. Therefore, its use is not recommended.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijpvm.ijpvm_164_23","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T12:02:33Z","timestamp":1738324953000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Associations of Opium Use with Metabolic Syndrome in Fasa PERSIAN Cohort Study: A Population-Based Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Rafat","family":"Shadmehr","sequence":"first","affiliation":[{"name":"Larestan Health Center, Larestan University of Medical Sciences, Larestan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Sharafi","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, 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Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdolmajid","family":"Ghasemian","sequence":"additional","affiliation":[{"name":"Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azizallah","family":"Dehghan","sequence":"additional","affiliation":[{"name":"Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1]]},"reference":[{"key":"R1-20250825","first-page":"51","article-title":"Metabolic syndrome and its associated risk factors in Iranian adults: A systematic review","volume":"6","author":"Hajian-Tilaki","year":"2015","journal-title":"Caspian J Internal Med"},{"key":"R2-20250825","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.tem.2021.04.008","article-title":"Links between metabolic syndrome 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