{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:25:30Z","timestamp":1787840730085,"version":"build-2784847793"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Inflammatory markers of blood are critical predictors of chronic diseases as well as exacerbating risk factors. Exercise is a well-known strategy to reduce the risk of inflammation and chronic disease. The present study aimed to investigate the anti-inflammatory effects of a period of aerobic training and vitamin D supplementation (AT + Vit D) in postmenopausal women with metabolic syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This quasi-experimental research was performed on forty-six patients with metabolic syndrome who were selected according to the available sampling method, and were randomly divided into four groups: AT + Vit D (50,000 IU), AT, Vit D (50,000 IU), and control (C). The training protocol consisted of 40\u201360 min of AT 60\u201375% of maximal heart rate, three times a week, for 8 weeks. One-way Analysis of variance (ANOVA) and\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test were used to compare the between and within groups; the Bonferroni\n                      <jats:italic toggle=\"yes\">post hoc<\/jats:italic>\n                      test was used if significant differences were found.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The combination of exercise and vitamin D significantly reduced C-reactive protein (CRP) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001), interleukin-6 (IL-6) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001), and improved the metabolic syndrome indices (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001 in all indices). The results also show that the improvement in the metabolic syndrome indices, CRP, and IL-6 was more significant in AT + Vit D, compared to AT or Vit D alone.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The findings from the present study suggested that a sedentary lifestyle and vitamin D deficiency accelerated the occurrence of metabolic syndrome probably by increasing the anti-inflammatory. Additionally, adequate levels of plasma vitamin D are necessary to achieve the beneficial metabolic effects of AT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpvm.ijpvm_312_20","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T09:07:10Z","timestamp":1716973630000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Anti-Inflammatory Effects of a Period of Aerobic Training and Vitamin D Supplementation in Postmenopausal Women with Metabolic Syndrome"],"prefix":"10.4103","volume":"13","author":[{"given":"Parivash Najafi","family":"Nazarabadi","sequence":"first","affiliation":[{"name":"Department of Physical Education and Sport Science, Sanandaj Branch, Islamic Azad University, Sunanda, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaher","family":"Etemad","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Science, Sanandaj Branch, Islamic Azad University, Sunanda, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rastegar","family":"Hoseini","sequence":"additional","affiliation":[{"name":"Department of Exercise Physiology, Faculty of Sport Sciences, Razi University, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatah","family":"Moradi","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Sciences, Saghez Branch, Islamic Azad University, Saghez, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,4,8]]},"reference":[{"key":"R1-20250813","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.dsx.2017.12.023","article-title":"Metabolic syndrome prevalence in the Iranian adult's general population and its trend: A systematic review and meta-analysis of observational studies","volume":"12","author":"Mokhayeri","year":"2018","journal-title":"Diabetes Metab Syndr"},{"key":"R2-20250813","article-title":"Serum adipokines and metabolic syndrome risk factors in hispanic children. 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