{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:23:07Z","timestamp":1787768587093,"version":"build-2784847793"},"reference-count":66,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Migraine is a prevalent disabling neurovascular condition with a high burden on society. The association between migraine and metabolic disorders, including type 2 diabetes mellitus (T2DM), is unclear. In this manuscript, we reviewed the association between migraine and T2DM. Results are summarized descriptively, and potential mechanisms are discussed. Included studies were cross-sectional (n = 6), case-control (n = 1), or cohort (n = 4). A mixed association between migraine and T2DM was reported: positive, inverse, and no association. Association between migraine and T2DM was suggested to follow an age-related trend: positive association in younger age, and negative in older age. Diabetes is associated with lifestyle modification, impaired vasodilation, neuropathy, and reduced calcitonin gene-related peptide, which might result in reduced headache. A rigorous cohort study with long follow-up is needed to establish the nature and strength of the association between migraine and T2DM.<\/jats:p>","DOI":"10.4103\/ijpvm.ijpvm_341_23","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T15:00:16Z","timestamp":1772031616000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["The Association Between Migraine and Type 2 Diabetes Mellitus: A Narrative Review"],"prefix":"10.4103","volume":"17","author":[{"given":"Faraidoon","family":"Haghdoost","sequence":"first","affiliation":[{"name":"The George Institute for Global Health, University of New South Wales (UNSW), Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Salam","sequence":"additional","affiliation":[{"name":"The George Institute for Global Health, University of New South Wales (UNSW), Sydney, Australia"},{"name":"The George Institute for Global Health, Hyderabad, Telangana, India"},{"name":"Prasanna School of Public Health, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Rodgers","sequence":"additional","affiliation":[{"name":"The George Institute for Global Health, University of New South Wales (UNSW), Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily R.","family":"Atkins","sequence":"additional","affiliation":[{"name":"The George Institute for Global Health, University of New South Wales (UNSW), Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2]]},"reference":[{"key":"R1-20260225","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S0140-6736(17)32154-2","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016","volume":"390","year":"2017","journal-title":"Lancet (London, England)"},{"key":"R2-20260225","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/S1474-4422(18)30322-3","article-title":"GH. 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