{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:20:24Z","timestamp":1787775624713,"version":"build-2784847793"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study aimed to evaluate the effect of hemoglobin (Hb) levels on 3-year clinical outcomes and long-term cardiovascular-related mortality in MI patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This study is a secondary study of the ST Elevation Myocardial Infarction Cohort Study (SEMI-CI) in Isfahan, Iran, that included 844 STEMI patients. The Hb level and other clinical and biochemical data during hospitalization were recorded at admission and also for 3 years annually. Cox regression analyses (univariate and multivariate) were performed to identify hazard ratios for CVD events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The prevalence of anemia was 16.7% in our population. Anemia was associated with an increased risk of the composite event (HR: 2.38, 95% CI: 1.77\u20133.19), mortality (HR: 2.91, 95% CI: 2.03\u20134.15), and unstable angina (HR: 2.22, 95% CI: 1.07\u20134.58) during a 3-year follow-up. After adjusting factors including smoking, diabetes, hypercholesterolemia, atrial fibrillation, treated hypertension, and BMI, anemia was only associated with an increased risk of the composite event and mortality. The 3-year cardiovascular survival curve showed better results in the nonanemic group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value &lt; 0.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Anemia was associated with a higher prevalence of 3-year mortality in STEMI patients, especially in the first year. In addition, there were associations between anemia and some CVD events in long-term follow-ups such as composite CVD events and unstable angina in our population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijpvm.ijpvm_92_24","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T06:00:38Z","timestamp":1760680838000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Anemia on Long-Term Outcomes and Mortality in ST-Segment Elevation Myocardial Infarction Patients: A SEMI-CI Cohort Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Masoumeh","family":"Sadeghi","sequence":"first","affiliation":[{"name":"Department of Cardiology, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatereh 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