{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T08:54:11Z","timestamp":1765356851717},"reference-count":48,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T00:00:00Z","timestamp":1626220800000},"content-version":"vor","delay-in-days":286,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian Journal of Radiology and Imaging"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Aims: Newer cardiac magnetic resonance techniques like native T1 mapping are being used increasingly as an adjunct to diagnose myocardial diseases with fibrosis. However, its full clinical utility has not been tested extensively, especially in the Indian population. The purpose of this study was to find native T1 values in healthy individuals without cardiac disease in our 3-Tesla MRI system and examine whether native myocardial T1 values can be used to differentiate between normal and diffuse myocardial disease groups. Subjects and Methods: After approval from the institutional ethics committee, native T1 mapping was performed in 12 healthy individuals without cardiac disease who served as controls and in 26 patients with diffuse myocardial diseases (acute myocarditis (n = 5), hypertrophic cardiomyopathy (HCM) (n = 8), nonischemic dilated cardiomyopathy (DCM) (n = 7), restrictive cardiomyopathy (RCM) due to amyloidosis (n = 6)) in a 3-Tesla MRI system in short axis slices and four-chamber view using a modified Look-Locker inversion recovery sequence. The mean native T1 values and standard deviations were calculated for control and disease groups and compared. The ability of native myocardial T1 mapping to differentiate between normal and diffuse myocardial disease groups was assessed. One-way ANOVA with Tukey\u2019s Post-Hoc test was used to find significant difference in the multivariate analysis and Chi-Square test was used to find the significance in categorical data. Results: The native T1 values for the healthy group in our 3-Tesla MRI system was 1186.47 \u00b1 45.67 ms. The mean T1 values of the groups acute myocarditis (1418.68 \u00b1 8.62 ms), HCM (1355.86 \u00b1 44.67 ms), nonischemic DCM (1341.31 \u00b1 41.48 ms), and RCM due to amyloidosis (1370.37 \u00b1 90.14 ms) were significantly higher (P = 0.0005) than that of the healthy control group. Conclusion: Native myocardial T1 mapping is a promising tool for differentiating between healthy and diffuse myocardial disease groups.<\/jats:p>","DOI":"10.4103\/ijri.ijri_326_20","type":"journal-article","created":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T18:26:02Z","timestamp":1610562362000},"page":"465-472","source":"Crossref","is-referenced-by-count":5,"title":["Native T1 mapping in diffuse myocardial diseases using 3-Tesla MRI: An institutional experience"],"prefix":"10.1055","volume":"30","author":[{"given":"Vimal Chacko","family":"Mondy","sequence":"additional","affiliation":[{"name":"Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S Babu","family":"Peter","sequence":"additional","affiliation":[{"name":"Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Ravi","sequence":"additional","affiliation":[{"name":"Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,7,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/0022-2828(90)90079-H","article-title":"Enhanced deposition of predominantly type I collagen in myocardial disease","volume":"22","author":"J E Bishop","year":"1990","journal-title":"J Mol Cell Cardiol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1136\/heart.89.10.1255","article-title":"Interstitial fibrosis in the dilated non-ischaemic myocardium","volume":"89","author":"A Brooks","year":"2003","journal-title":"Heart"},{"key":"ref3","first-page":"303","article-title":"The extracellular matrix in the failing human 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Luetkens","year":"2014","journal-title":"Radiology"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/jmri.25885","article-title":"Native T1 reference values for nonischemic cardiomyopathies and populations with increased cardiovascular risk: A systematic review and meta-analysis","volume":"47","author":"M van den Boomen","year":"2018","journal-title":"J Magn Reson Imaging"}],"container-title":["Indian Journal of Radiology and 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