{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:32:30Z","timestamp":1786739550756,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Papulonecrotic tuberculid (PNT) is a rare hypersensitivity reaction to\n                    <jats:italic toggle=\"yes\">Mycobacterium tuberculosis<\/jats:italic>\n                    , typically seen in immunocompetent individuals but occasionally reported in human immunodeficiency virus (HIV)-positive patients. We describe the case of a 30-year-old HIV-positive male with high-risk sexual behavior presenting with crusted papulopustular lesions and severe headache. Cerebrospinal fluid and venereal disease research laboratory (VDRL) were positive for VDRL and treponema pallidum hemagglutination confirming neurosyphilis, while skin biopsy revealed PNT. This case underscores the diagnostic challenge of differentiating co-infections and id reactions in HIV. The patient improved significantly with anti-tubercular therapy and benzylpenicillin.\n                  <\/jats:p>","DOI":"10.4103\/ijstd.ijstd_110_25","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:00:11Z","timestamp":1769788811000},"page":"45-47","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Papulonecrotic tuberculid mimicking lues maligna in an immunocompromised male"],"prefix":"10.4103","volume":"47","author":[{"given":"Saransh","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaishnavi","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudheer Kumar","family":"Arava","sequence":"additional","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somesh","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"R1-20260626","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/1098-2825(2000)14:4<133::AID-JCLA1>3.0.CO;2-7","article-title":"Detection of mycobacterial DNA in papulonecrotic tuberculid lesions by polymerase chain reaction","volume":"14","author":"Quir\u00f3s","year":"2000","journal-title":"J Clin Lab Anal"},{"key":"R2-20260626","doi-asserted-by":"crossref","first-page":"S154","DOI":"10.1016\/j.jaad.2005.01.110","article-title":"Nodular tuberculid in a patient with HIV","volume":"53","author":"Friedman","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"R3-20260626","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1468-3083.2004.00842.x","article-title":"Papulonecrotic tuberculid in a human immunodeficiency virus type-1 patient with multidrug-resistant tuberculosis","volume":"18","author":"Fernandes","year":"2004","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R4-20260626","doi-asserted-by":"crossref","first-page":"320","DOI":"10.4103\/idoj.idoj_284_22","article-title":"Tuberculids: A narrative review","volume":"14","author":"Dhattarwal","year":"2023","journal-title":"Indian Dermatol Online J"},{"key":"R5-20260626","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1097\/OLQ.0b013e3181a2a946","article-title":"Lues maligna in early HIV infection case report and review of the literature","volume":"36","author":"Tucker","year":"2009","journal-title":"Sex Transm Dis"}],"container-title":["Indian Journal of Sexually Transmitted Diseases and AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijstd.ijstd_110_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:29:56Z","timestamp":1786735796000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijstd.ijstd_110_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijstd.ijstd_110_25","relation":{},"ISSN":["2589-0557","2589-0565"],"issn-type":[{"value":"2589-0557","type":"print"},{"value":"2589-0565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-05-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}