{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:25:03Z","timestamp":1787757903377,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"\n Introduction:<\/jats:title>\n Lichen sclerosus (LS) is a chronic dermatosis frequently located over labial, perineal, and perianal areas. The etiology is multifactorial and includes genetic, autoimmune, hormonal, and infectious aspects.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n A series of twenty genital LS patients was carried out to evaluate the signs, symptoms, complications, and affliction of quality of life.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Eighteen out of twenty patients were female between 30 and 73 years and showed smooth, glistening, and whitish plaques. The mean duration was 8.4 years. Itching and burning was the most common symptom (75%) corresponding to excoriation and fissuring of genitalia (75%). Malignancy was seen in two cases (10%). The mean Vulvar Quality of Life Index was 9.2, higher in younger patients.<\/jats:p>\n <\/jats:sec>\n \n Discussion:<\/jats:title>\n LS is a disorder of older age group with female preponderance. It is a source of significant morbidity, and long-standing cases predispose to vulvar malignancy.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n To conclude, early diagnosis with proper counselling of the patient and his\/her partner regarding various aspects of disease are essential for a wholesome approach.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijstd.ijstd_126_20","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T06:17:59Z","timestamp":1654496279000},"page":"43-46","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India"],"prefix":"10.4103","volume":"43","author":[{"given":"Sukhmani Kaur","family":"Brar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubeena","family":"Bano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neerja","family":"Puri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amarbir","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-8-20240831","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-0560.1976.tb01105.x","article-title":"New nomenclature for vulvar disease","volume":"3","author":"Kaufman","year":"1976","journal-title":"J Cutan Pathol"},{"key":"R2-8-20240831","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/j.1365-2133.2010.09997.x","article-title":"British Association of dermatologists\u2019 guidelines for the management of lichen sclerosus 2010","volume":"163","author":"Neill","year":"2010","journal-title":"Br J Dermatol"},{"key":"R3-8-20240831","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/S0140-6736(98)08228-2","article-title":"Lichen sclerosus","volume":"353","author":"Powell","year":"1999","journal-title":"The Lancet"},{"key":"R4-8-20240831","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0190-9622(95)90060-8","article-title":"Lichen sclerosus","volume":"32","author":"Meffert","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"R5-8-20240831","first-page":"9","article-title":"Lichen sclerosus et atrophicus","volume":"57","author":"Wallace","year":"1971","journal-title":"Trans St Johns Hosp Dermatol Soc"},{"key":"R6-8-20240831","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1001\/archderm.136.3.350","article-title":"Circumcision and genital dermatoses","volume":"136","author":"Mallon","year":"2000","journal-title":"Arch Dermatol"},{"key":"R7-8-20240831","first-page":"477","article-title":"Prevalence of vulvar lichen sclerosus in a general gynecology practices","volume":"50","author":"Goldstein","year":"2005","journal-title":"J Reprod Med"},{"key":"R8-8-20240831","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1001\/archderm.140.6.702","article-title":"Does treatment of vulvar lichen sclerosus influence its prognosis?","volume":"140","author":"Cooper","year":"2004","journal-title":"Arch Dermatol"},{"key":"R9-8-20240831","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/ajd.13235","article-title":"Vulvar Quality of Life Index (VQLI)-A simple tool to measure quality of life in patients with vulvar disease","volume":"61","author":"Saunderson","year":"2020","journal-title":"Australas J Dermatol"},{"key":"R10-8-20240831","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/ajd.13197","article-title":"The Vulval Disease Quality of Life Index in women with vulval lichen sclerosus correlates with clinician and symptom scores","volume":"61","author":"Felmingham","year":"2020","journal-title":"Australas J Dermatol"},{"key":"R11-8-20240831","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1177\/014107689608901210","article-title":"Anogenital lichen sclerosus in women","volume":"89","author":"Thomas","year":"1996","journal-title":"J R Soc Med"},{"key":"R12-8-20240831","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/S0046-8177(98)90198-8","article-title":"Vulvar lichen sclerosus and squamous cell carcinoma: A cohort, case control, and investigational study with historical perspective; 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