{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:31:31Z","timestamp":1786739491503,"version":"build-2736575974"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Syphilis, a genito-ulcerative disease caused by the organism\n                      <jats:italic toggle=\"yes\">Treponema pallidum<\/jats:italic>\n                      subspecies\n                      <jats:italic toggle=\"yes\">pallidum<\/jats:italic>\n                      , is renowned for its invasiveness and immune - evasiveness if untreated. Historical reports from the 15\n                      <jats:sup>th<\/jats:sup>\n                      century indicate that syphilis was perceived as a dangerous infection, and a source of public alarm via fear of contagion and dread of its manifestations. It has varied and subtle features that makes clinical diagnosis difficult and leads to many infections being unrecognised. The total number of reported cases of syphilis (all stages) increased 13.3% during 2017-2018. WHO estimates that each year 11 million new cases of syphilis occur globally among adults of 15-49 years of age. In our retrospective study, we analysed trends of syphilis in different groups of patients attending our tertiary care centre and reviewed the increase in disease pattern with varied clinical presentations. It is important for the medical practioners to be vigilant to look out for usual as well as unusual presentation of the great imitator.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijstd.ijstd_12_18","type":"journal-article","created":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T06:00:24Z","timestamp":1627365624000},"page":"171-174","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Clinicodemographic profile of syphilis with rising trends at a tertiary care hospital"],"prefix":"10.4103","volume":"42","author":[{"given":"A. P.","family":"Gosavi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravindranath B.","family":"Chavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akanksha","family":"Bandhade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drashana R.","family":"Kundale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-17-20240831","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1001\/archinternmed.2012.2706","article-title":"Effect of early syphilis infection on plasma viral load and CD4 cell count in human immunodeficiency virus-infected men: Results from the FHDH-ANRS CO4 cohort","volume":"172","author":"Jarzebowski","year":"2012","journal-title":"Arch Intern Med"},{"key":"R2-17-20240831","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1097\/00002030-200410210-00012","article-title":"Syphilis increases HIV viral load and decreases CD4 cell counts in HIV-infected patients with new syphilis infections","volume":"18","author":"Buchacz","year":"2004","journal-title":"AIDS"},{"key":"R3-17-20240831","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/sti.75.1.3","article-title":"From epidemiological synergy to public health policy and practice: The contribution of other sexually transmitted diseases to sexual transmission of HIV infection","volume":"75","author":"Fleming","year":"1999","journal-title":"Sex Transm Infect"},{"key":"R5-17-20240831","first-page":"60","article-title":"The value of penicillin alone in the prevention and treatment of congenital syphilis","volume":"31","author":"Ingraham","year":"1950","journal-title":"Acta Derm Venereol Suppl (Stockh"}],"container-title":["Indian Journal of Sexually Transmitted Diseases and AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijstd.IJSTD_12_18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:29:22Z","timestamp":1786735762000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijstd.IJSTD_12_18"}},"subtitle":["The tip of the iceberg"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":4,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijstd.ijstd_12_18","relation":{},"ISSN":["2589-0557"],"issn-type":[{"value":"2589-0557","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}