{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:23:27Z","timestamp":1787844207534,"version":"build-2784847793"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Treatment adherence to antiretroviral treatment (ART) is critical in reducing morbidity, mortality, and improving the survival in HIV patients. ART is a life-long commitment, and the variety of factors can influence treatment adherence. We studied the factors affecting treatment adherence in the private sector and public sector outdoor clinic in Ahmedabad, India. The primary objective of this study is to compare the level of adherence and factors that influence adherence to ART in patients attending government run free ART program and private setup.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a cross-sectional study of 8 weeks among HIV-infected patients who were receiving ART from private clinic and free ART center from July 2019 to September 2019. We enrolled all consecutive patients &gt;18 years of age attending both clinics. Statistical analysis was carried out using the SPSS software version 25.0. Multiple logistic regression was used to identify the factors that were independently associated with adherence to ART.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study enrolled 306 patients, 151 (49.34%) from the outpatient department of private hospital, and 155 (50.65%) from the free ART center. Patients attending private clinics were more likely to have been diagnosed with HIV since \u226510 years compared to free ART center. Higher opportunistic infection rates were found in free ART center (64.51%). Treatment adherence was significantly lower in the patients attending free ART center (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.004). Patients taking concomitant medications for other comorbid conditions (\u22654 pills\/day) were more likely to exhibit inadequate adherence ([odds ratio] 1.216, 95% confidence interval 1.0171\u20131.454). Univariate analysis showed that age, education, habits of alcohol, tobacco, number of pills, and duration of disease played a significant role in predicting adherence to ART (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients attending private clinic are surviving longer with HIV diagnosis, have fewer opportunistic infections, and have better treatment adherence compared to free ART clinic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijstd.ijstd_22_20","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T03:24:38Z","timestamp":1620012278000},"page":"62-68","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of self-reported adherence to ART and patient's virological\/CD4 response in a tertiary care clinic and government free ART clinic"],"prefix":"10.4103","volume":"42","author":[{"given":"Rushin","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amee","family":"Pandya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ketan K","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supriya","family":"Malhotra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul K","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20240831","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1056\/NEJMoa1105243","article-title":"Prevention of HIV-1 infection with early antiretroviral therapy","volume":"365","author":"Cohen","year":"2011","journal-title":"N Engl J Med"},{"key":"R2-11-20240831","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1001\/jama.2016.5148","article-title":"Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy","volume":"316","author":"Rodger","year":"2016","journal-title":"JAMA"},{"key":"R4-11-20240831","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/0253-7184.74971","article-title":"Quality of life in HIV\/AIDS","volume":"31","author":"Basavaraj","year":"2010","journal-title":"Indian J Sex Transm Dis AIDS"},{"key":"R5-11-20240831","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1080\/09540120412331305098","article-title":"Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherence","volume":"17","author":"Mannheimer","year":"2005","journal-title":"AIDS Care"},{"key":"R6-11-20240831","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1080\/09540120050042891","article-title":"Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG Adherence Instruments","volume":"12","author":"Chesney","year":"2000","journal-title":"AIDS Care"},{"key":"R7-11-20240831","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1472-6963-10-42","article-title":"Measuring adherence to antiretroviral treatment in resource-poor settings: The clinical validity of key indicators","volume":"10","author":"Ross-Degnan","year":"2010","journal-title":"BMC Health Serv Res"},{"key":"R8-11-20240831","doi-asserted-by":"crossref","first-page":"e0154893","DOI":"10.1371\/journal.pone.0154893","article-title":"What is required to end the AIDS epidemic as a public health threat by 2030? 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