{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:22:24Z","timestamp":1787764944560,"version":"build-2784847793"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"\n Introduction:<\/jats:title>\n Dermatological manifestations are common manifestations of human immunodeficiency virus (HIV) disease, seen in 80% to 95% of HIV-infected patients. Dermatological manifestations are considered clinical indicators to predict and assess the underlying immune status.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n This study aims to document the dermatological manifestations in relation to CD4 count in people living with HIV (PLHIV).<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n Cross-sectional study in 250 PLHIV fulfilling inclusion\u2013exclusion criteria was conducted. Variables including sociodemographic profile, recent CD4 count (data from antiretroviral therapy center), and dermatological manifestation (physical examination) were collected. Clinical diagnosis was established, and patients were grouped according to the World Health Organization immunological staging<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Majority of PLHIV (39.6%) were in the age group of 31\u201340 years. Males were affected more than females (1.6:1). A total of 364 dermatoses were observed; dermatological manifestation per patient ranged from 1 to 4. 32.80%. PLHIV had CD4 count >500 cells\/mm\n 3<\/jats:sup>\n , 15.60% had CD4 count between 200\u2013349 cells\/mm\n 3<\/jats:sup>\n . Majority of dermatosis had infectious etiology (77.6%), out of which dermatophytosis (27.2%) was the most common infectious condition, whereas pruritic papular eruption was the most common (11.6%) noninfectious condition. A statistically significant association of CD4 count was found with dermatophytosis (\n P<\/jats:italic>\n \u2264 0.001) and candidiasis (\n P<\/jats:italic>\n = 0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n The study showed a significant association between the number of dermatological manifestation and CD4 count as majority of study participants (67.2%) had CD4 <500 cells\/mm\n 3<\/jats:sup>\n at the time of episode of dermatosis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijstd.ijstd_24_23","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T03:50:57Z","timestamp":1701748257000},"page":"147-151","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Association of dermatological manifestations with CD4 count among people living with HIV attending tertiary care hospital of South Gujarat"],"prefix":"10.4103","volume":"44","author":[{"given":"Brijesh Vinubhai","family":"Parmar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Purohit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20240831","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1001\/archderm.134.10.1208","article-title":"Prevalence of cutaneous disorders in a population of HIV-infected patients. Southwestern France, 1996. Groupe d'Epid\u00e9miologie Clinique du SIDA en Aquitaine","volume":"134","author":"Spira","year":"1998","journal-title":"Arch Dermatol"},{"key":"R2-9-20240831","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1097\/QAD.0b013e328354622a","article-title":"The evolving epidemiology of HIV\/AIDS","volume":"26","author":"De Cock","year":"2012","journal-title":"AIDS"},{"key":"R4-9-20240831","first-page":"247","article-title":"Learning lessons through data triangulation: Vulnerability of Surat City to HIV epidemic","volume":"4","author":"Modi","year":"2013","journal-title":"Natl J Community Med"},{"key":"R5-9-20240831","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4103\/ijstd.IJSTD_130_15","article-title":"Correlating CD4 count with mucocutaneous manifestations in HIV-positive patients: A prospective study","volume":"38","author":"Chandrakala","year":"2017","journal-title":"Indian J Sex Transm Dis AIDS"},{"key":"R6-9-20240831","doi-asserted-by":"crossref","first-page":"19","DOI":"10.4103\/0253-7184.112865","article-title":"Pattern of mucocutaneous manifestations in human immunodeficiency virus-positive patients in North India","volume":"34","author":"Kore","year":"2013","journal-title":"Indian J Sex Transm Dis AIDS"},{"key":"R7-9-20240831","doi-asserted-by":"crossref","first-page":"338","DOI":"10.4103\/0019-5154.57609","article-title":"Dermatological manifestations in HIV-infected patients at a tertiary care hospital in a tribal (Bastar) region of Chhattisgarh, India","volume":"54","author":"Singh","year":"2009","journal-title":"Indian J Dermatol"},{"key":"R8-9-20240831","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4103\/0253-7184.120538","article-title":"Dermatological manifestations in human immunodeficiency virus infected patients: Morphological spectrum with CD4 correlation","volume":"34","author":"Chawhan","year":"2013","journal-title":"Indian J Sex Transm Dis AIDS"},{"key":"R9-9-20240831","doi-asserted-by":"crossref","first-page":"146","DOI":"10.4103\/ijstd.IJSTD_69_18","article-title":"Prevalence of pruritic papular eruption among HIV patients: A cross-sectional study","volume":"40","author":"Mohammed","year":"2019","journal-title":"Indian J Sex Transm Dis AIDS"},{"key":"R10-9-20240831","doi-asserted-by":"crossref","first-page":"501","DOI":"10.4103\/0378-6323.44318","article-title":"Pruritic papular eruptions of HIV: A clinicopathologic and therapeutic study","volume":"74","author":"Lakshmi","year":"2008","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R11-9-20240831","doi-asserted-by":"crossref","first-page":"166","DOI":"10.4103\/0253-7184.167160","article-title":"Effect of antiretroviral therapy on mucocutaneous manifestations among human immunodeficiency virus-infected patients in a tertiary care centre in South India","volume":"36","author":"Prabhakaran","year":"2015","journal-title":"Indian J Sex Transm Dis AIDS"},{"key":"R12-9-20240831","first-page":"82","article-title":"Mucocutaneous manifestations of HIV infection","volume":"70","author":"Shobhana","year":"2004","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R13-9-20240831","doi-asserted-by":"crossref","first-page":"227","DOI":"10.4103\/ijd.IJD_206_17","article-title":"The great Indian epidemic of superficial dermatophytosis: An appraisal","volume":"62","author":"Verma","year":"2017","journal-title":"Indian J Dermatol"}],"container-title":["Indian Journal of Sexually Transmitted Diseases and AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijstd.ijstd_24_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:52:41Z","timestamp":1787763161000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijstd.ijstd_24_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijstd.ijstd_24_23","relation":{},"ISSN":["2589-0557"],"issn-type":[{"value":"2589-0557","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]}}}