{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:32:19Z","timestamp":1787841139575,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Sarcoidosis is a granulomatous disease that can affect multiple organs, with cutaneous manifestations occurring in about 25% of patients. Tattooing, including the newer technique of eyebrow micropigmentation, is known to trigger sarcoidosis in genetically predisposed individuals. This study reviews the case of a 55-year-old female who developed sarcoidal reaction (SR) on her eyebrows 3 years after undergoing micropigmentation. The patient presented with erythematous, scaly plaques and partial madarosis. A biopsy-confirmed cutaneous SR and systemic disease was ruled out. Treatment involved intralesional corticosteroids followed by systemic therapy with hydroxychloroquine and oral prednisone, leading to clinical improvement. The case highlights the potential for micropigmentation to induce SR, emphasizing the importance of early diagnosis and a multidisciplinary approach. Dermatologists should be vigilant in recognizing cutaneous SR in patients with new-onset skin lesions after micropigmentation and consider both local and systemic treatments based on disease severity. This case also underscores the psychosocial impact of facial involvement, emphasizing the need for comprehensive care.<\/jats:p>","DOI":"10.4103\/ijt.ijt_114_24","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:01:59Z","timestamp":1762250519000},"page":"151-153","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Sarcoidal Reaction of the Eyebrows after Micropigmentation: A Review of Therapeutic Approaches"],"prefix":"10.4103","volume":"17","author":[{"given":"Marinna Sampaio","family":"Campos","sequence":"first","affiliation":[{"name":"Department of Dermatology, Funda\u00e7\u00e3o Lus\u00edada, Santos, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loanda Oliveira","family":"Fukuma","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Funda\u00e7\u00e3o Lus\u00edada, Santos, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Carvalho","family":"Delgado","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Funda\u00e7\u00e3o Lus\u00edada, Santos, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla Cala\u00e7a Kabbach","family":"Prigenzi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Funda\u00e7\u00e3o Lus\u00edada, Santos, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Lopes Mattos E","family":"Dinato","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Funda\u00e7\u00e3o Lus\u00edada, Santos, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hudson Dutra","family":"Rezende","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Funda\u00e7\u00e3o Lus\u00edada, Santos, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"R1-20251105","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1684\/ejd.2018.3347","article-title":"Systemic sarcoidosis revealed by sarcoidal granulomas on eyebrow tattoos","volume":"28","author":"Wang","year":"2018","journal-title":"Eur J Dermatol"},{"key":"R2-20251105","article-title":"Eyebrow tattoo-associated sarcoidosis: A case report","volume":"9","author":"Nie","year":"2022","journal-title":"Fron Med"},{"key":"R3-20251105","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1111\/jocd.13695","article-title":"Koebnerization secondary to microblading","volume":"20","author":"Tierney","year":"2021","journal-title":"J Cosmet Dermatol"},{"key":"R4-20251105","article-title":"Cutaneous sarcoidosis in eyebrows cosmetically pigmented with microblading method: A case report and review of the 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