{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:34:49Z","timestamp":1790109289071,"version":"4.0.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Androgenetic alopecia (AGA), although considered medically benign, has been found to be associated with increased cardiovascular risk, especially in patients with early onset (\u2264 30 years). Metabolic syndrome (MetS) comprises a cluster of cardiovascular risk factors predicting morbidity. Very few studies focused on early development of MetS in younger males and the association with the severity of AGA, necessitating further research.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To estimate the prevalence of MetS in men with early-onset AGA and to assess if there is a positive correlation between the severity of AGA and the development of MetS and its components.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study was undertaken in a tertiary care hospital from November 2020 to October 2022, on men in the age group of 18 \u2013 40 years. 100 men with early-onset AGA (\u2264 30 years) were included in the study. MetS was diagnosed as per the criteria by the International Diabetes Federation (IDF), and American Heart Association\/ National Heart, Lung and Blood Institute (AHA\/NHLBI). Chi-square test and student\u2019s t-test were used for statistical analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Metabolic syndrome was diagnosed in 63 (63%) of the patients. The prevalence of MetS (P = 0.006), elevated waist circumference (P = 0.006), elevated serum triglycerides (P = 0.011), and mean value of serum high-density lipoprotein (P = 0.05) was statistically significant in patients with severe AGA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A high prevalence of metabolic syndrome was found in young males with early-onset AGA. Screening and lifestyle modifications should be enforced earlier to lessen cardiovascular morbidity and mortality in young male patients with AGA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijt.ijt_135_23","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T15:00:09Z","timestamp":1750690809000},"page":"36-41","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Is Early-onset Androgenetic Alopecia Associated with Metabolic Syndrome? \u2013 A Descriptive Cross-sectional Study"],"prefix":"10.4103","volume":"17","author":[{"given":"Sheena","family":"Majella","sequence":"first","affiliation":[{"name":"Department of Dermatology, St. John\u2019s Medical College Hospital, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Aithal","sequence":"additional","affiliation":[{"name":"Department of Dermatology, St. 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