{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:32:02Z","timestamp":1786735922926,"version":"build-2736575974"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Trichol"],"published-print":{"date-parts":[[2019]]},"DOI":"10.4103\/ijt.ijt_76_19","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T08:47:28Z","timestamp":1571215648000},"page":"185","source":"Crossref","is-referenced-by-count":22,"title":["What's new in the pathophysiology of alopecia areata? the possible contribution of skin and gut microbiome in the pathogenesis of alopecia \u2013 Big opportunities, big challenges, and novel perspectives"],"prefix":"10.4103","volume":"11","author":[{"given":"Kamila","family":"Migacz-Gruszka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Branicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksander","family":"Obtulowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Pirowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krystian","family":"Gruszka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Wojas-Pelc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0974-7753.269362-1","first-page":"215","volume-title":"A framework for human microbiome research","author":"Human","year":"2012","journal-title":"Nature"},{"key":"key-10.4103\/0974-7753.269362-2","first-page":"227","volume-title":"The gut microbiota \u2013 Masters of host development and physiology","author":"Sommer","year":"2013","journal-title":"Nat Rev Microbiol"},{"key":"key-10.4103\/0974-7753.269362-3","first-page":"75","volume-title":"The microbiota in adaptive immune homeostasis and disease","author":"Honda","year":"2016","journal-title":"Nature"},{"key":"key-10.4103\/0974-7753.269362-4","first-page":"87","volume-title":"Gut microbiota, immune development and function","author":"Bengmark","year":"2013","journal-title":"Pharmacol Res"},{"key":"key-10.4103\/0974-7753.269362-5","first-page":"4","volume-title":"The role of gut microbiota in immune homeostasis and autoimmunity","author":"Wu","year":"2012","journal-title":"Gut Microbes"},{"key":"key-10.4103\/0974-7753.269362-6","first-page":"363","volume-title":"Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota","author":"Peterson","year":"2015","journal-title":"Clin Exp Immunol"},{"key":"key-10.4103\/0974-7753.269362-7","first-page":"1000","volume-title":"Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease","author":"Palm","year":"2014","journal-title":"Cell"},{"key":"key-10.4103\/0974-7753.269362-8","first-page":"541","volume-title":"Innate and adaptive humoral responses coat distinct commensal bacteria with immunoglobulin A","author":"Bunker","year":"2015","journal-title":"Immunity"},{"key":"key-10.4103\/0974-7753.269362-9","first-page":"36","volume-title":"Crosstalk at the mucosal border: Importance of the gut microenvironment in IBS","author":"\u00d6hman","year":"2015","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"key-10.4103\/0974-7753.269362-10","first-page":"206","volume-title":"Microbial dysbiosis in common variable immune deficiencies: Evidence, causes, and consequences","author":"Berbers","year":"2017","journal-title":"Trends Immunol"},{"key":"key-10.4103\/0974-7753.269362-11","first-page":"351732","volume-title":"Selected aspects in the pathogenesis of autoimmune diseases","author":"Nagy","year":"2015","journal-title":"Mediators Inflamm"},{"key":"key-10.4103\/0974-7753.269362-12","first-page":"1459","volume-title":"The gut microbiome as a major regulator of the gut-skin axis","author":"Salem","year":"2018","journal-title":"Front Microbiol"},{"key":"key-10.4103\/0974-7753.269362-13","first-page":"354","volume-title":"Microbiome in the gut-skin axis in atopic dermatitis","author":"Lee","year":"2018","journal-title":"Allergy Asthma Immunol Res"},{"key":"key-10.4103\/0974-7753.269362-14","first-page":"1115","volume-title":"Compartmentalized control of skin immunity by resident commensals","author":"Naik","year":"2012","journal-title":"Science"},{"key":"key-10.4103\/0974-7753.269362-15","first-page":"503","volume-title":"Alopecia areata and the gut-the link opens up for novel therapeutic interventions","author":"Borde","year":"2018","journal-title":"Expert Opin Ther Targets"},{"key":"key-10.4103\/0974-7753.269362-16","first-page":"1586","volume-title":"The changing landscape of alopecia areata: The translational landscape","author":"Wang","year":"2017","journal-title":"Adv Ther"},{"key":"key-10.4103\/0974-7753.269362-17","first-page":"17011","volume-title":"Messenger AG, Christiano AM, Sundberg JP.Alopecia areata","author":"Pratt","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"key-10.4103\/0974-7753.269362-18","first-page":"3","volume-title":"Alopecia areata: What's new in epidemiology, pathogenesis, diagnosis, and therapeutic options?","author":"Dainichi","year":"2017","journal-title":"J Dermatol Sci"},{"key":"key-10.4103\/0974-7753.269362-19","first-page":"e404","volume-title":"Alopecia areata.Current situation and perspectives","author":"Ju\u00e1rez-Rend\u00f3n","year":"2017","journal-title":"Arch Argent Pediatr"},{"key":"key-10.4103\/0974-7753.269362-20","first-page":"787","volume-title":"The role of cytokines and chemokines in the T-cell-mediated autoimmune process in alopecia areata","author":"Ito","year":"2014","journal-title":"Exp Dermatol"},{"key":"key-10.4103\/0974-7753.269362-21","first-page":"e107","volume-title":"Hair growth in two alopecia patients after fecal microbiota transplant","author":"Rebello","year":"2017","journal-title":"ACG Case Rep J"},{"key":"key-10.4103\/0974-7753.269362-22","first-page":"1","volume-title":"Alopecia areata: Disease characteristics, clinical evaluation, and new perspectives on pathogenesis","author":"Strazzulla","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"key-10.4103\/0974-7753.269362-23","first-page":"1043","volume-title":"Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition","author":"Xing","year":"2014","journal-title":"Nat Med"},{"key":"key-10.4103\/0974-7753.269362-24","first-page":"5966","volume-title":"Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci","author":"Betz","year":"2015","journal-title":"Nat Commun"},{"key":"key-10.4103\/0974-7753.269362-25","first-page":"919","volume-title":"Immunochip-based analysis: High-density genotyping of immune-related loci sheds further light on the autoimmune genetic architecture of alopecia areata","author":"Redler","year":"2015","journal-title":"J Invest Dermatol"},{"key":"key-10.4103\/0974-7753.269362-26","first-page":"2192","volume-title":"Follow-up study of the first genome-wide association scan in alopecia areata: IL13 and KIAA0350 as susceptibility loci supported with genome-wide significance","author":"Jagielska","year":"2012","journal-title":"J Invest Dermatol"},{"key":"key-10.4103\/0974-7753.269362-27","first-page":"1527","volume-title":"Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H\/HeJ mouse model","author":"Zhang","year":"2009","journal-title":"J Invest Dermatol"},{"key":"key-10.4103\/0974-7753.269362-28","first-page":"388","volume-title":"Increased history of childhood and lifetime traumatic events among adults with alopecia areata","author":"Willemsen","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"key-10.4103\/0974-7753.269362-29","first-page":"30","volume-title":"Dietary soy oil content and soy-derived phytoestrogen genistein increase resistance to alopecia areata onset in C3H\/HeJ mice","author":"McElwee","year":"2003","journal-title":"Exp Dermatol"}],"container-title":["International Journal of Trichology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:35:04Z","timestamp":1786732504000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijt.ijt_76_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019]]}},"alternative-id":["269362"],"URL":"https:\/\/doi.org\/10.4103\/ijt.ijt_76_19","relation":{},"ISSN":["0974-7753"],"issn-type":[{"value":"0974-7753","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}