{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:04:29Z","timestamp":1787169869981,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>An emerging treatment modality whose established efficacy in systemic inflammatory diseases is now being actively explored for cutaneous disorders: tofacitinib, an oral Janus kinase inhibitor, is one such treatment. Alopecia universalis has been reported to improve with the use of tofacitinib in various case reports and case series. Nail dystrophy is a diverse skin disorder that has been linked to autoimmune illnesses such as psoriasis and psoriatic arthritis in certain subtypes. Alopecia areata and alopecia universalis are also commonly associated with nail dystrophy. In the present case report, we see that there are also improvements in nail dystrophy in the patient with alopecia universalis who is using tofacitinib.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijt.ijt_91_21","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T08:01:09Z","timestamp":1637308869000},"page":"32-33","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Recovery of Alopecia Universalis with Associated Nail Dystrophy Treated with Tofacitinib"],"prefix":"10.4103","volume":"13","author":[{"given":"Vineet","family":"Dube","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20240903","doi-asserted-by":"crossref","first-page":"7194270","DOI":"10.1155\/2020\/7194270","article-title":"Prevalence and clinical characteristics of alopecia areata at a Tertiary Care Center in Saudi Arabia","volume":"2020","author":"Alshahrani","year":"2020","journal-title":"Dermatol Res Pract"},{"key":"R2-6-20240903","doi-asserted-by":"crossref","first-page":"250","DOI":"10.4103\/idoj.IDOJ_451_20","article-title":"Clinico-epidemiological profile of childhood alopecia areata along with dermoscopic correlation: A cross-section, observational study","volume":"12","author":"Bhardwaj","year":"2021","journal-title":"Indian Dermatol Online J"},{"key":"R3-6-20240903","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1111\/ijd.13866","article-title":"Nail changes in alopecia areata: An update and review","volume":"57","author":"Chelidze","year":"2018","journal-title":"Int J Dermatol"},{"key":"R4-6-20240903","first-page":"38","article-title":"JAK inhibitors for the treatment of alopecia areata","volume":"159","author":"Ramot","year":"2020","journal-title":"Harefuah"},{"key":"R5-6-20240903","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4103\/ijt.ijt_21_18","article-title":"Tofacitinib (Selective Janus Kinase Inhibitor 1 and 3): A promising therapy for the treatment of alopecia areata: A case report of six patients","volume":"10","author":"Shivanna","year":"2018","journal-title":"Int J Trichology"},{"key":"R6-6-20240903","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1001\/jamadermatol.2015.3772","article-title":"Tofacitinib citrate for the treatment of nail dystrophy associated with alopecia universalis","volume":"152","author":"Dhayalan","year":"2016","journal-title":"JAMA Dermatol"},{"key":"R7-6-20240903","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s10067-017-3574-0","article-title":"Recovery of nail dystrophy potential new therapeutic indication of tofacitinib","volume":"36","author":"Jaller","year":"2017","journal-title":"Clin Rheumatol"},{"key":"R8-6-20240903","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1159\/000445544","article-title":"Trachyonychia and twenty-nail dystrophy: A comprehensive review and discussion of diagnostic accuracy","volume":"2","author":"Jacobsen","year":"2016","journal-title":"Skin Appendage Disord"},{"key":"R9-6-20240903","first-page":"42","article-title":"Koilonychia in a patient with alopecia areata","volume":"14","author":"Litaiem","year":"2021","journal-title":"J Clin Aesthet Dermatol"}],"container-title":["International Journal of Trichology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijt.ijt_91_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:14:19Z","timestamp":1787166859000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijt.ijt_91_21"}},"subtitle":["A 6-year-old Child's Case Report"],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijt.ijt_91_21","relation":{},"ISSN":["0974-7753"],"issn-type":[{"value":"0974-7753","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}