{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:04:39Z","timestamp":1787169879255,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Primitive neuroectodermal tumor (PNET)\/Ewing's sarcoma tumors are a group of highly malignant tumors composed of small, round cells showing neuroectodermal differentiation that commonly affects soft tissue and bone. PNET involving the genitourinary system is rare and PNET of the penile urethra is rarer still. It exhibits a highly aggressive biological behavior with poor prognosis. We report a case of a 27-year-old male presenting with penile swelling and difficulty in passing urine. Examination revealed a firm penile urethral mass. Pathological and immunohistochemical results of the specimen obtained from urethroscopic biopsy followed by total penectomy confirmed the diagnosis of PNET of the urethra. He received combination chemotherapy: ifosfamide and etoposide (IE) + vincristine, Adriamycin, and cyclophosphamide (VAC). In conclusion, PNET has to be considered in the differential diagnosis of a penile urethral mass in young patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/iju.iju_178_20","type":"journal-article","created":{"date-parts":[[2023,8,12]],"date-time":"2023-08-12T06:12:09Z","timestamp":1691820729000},"page":"84-86","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Primitive neuroectodermal tumor of the penile urethra"],"prefix":"10.4103","volume":"37","author":[{"given":"Ashishkumar Narsinhbhai","family":"Asari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijal","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. B.","family":"Yuvaraja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-16-20240903","doi-asserted-by":"crossref","first-page":"386","DOI":"10.4103\/0377-4929.42518","article-title":"Primitive neuroectodermal tumor of prostate","volume":"51","author":"Kumar","year":"2008","journal-title":"Indian J Pathol Microbiol"},{"key":"R2-16-20240903","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1136\/jcp.2005.029199","article-title":"Primary primitive neuroectodermal tumour of the urinary bladder: A clinico-pathological study emphasising immunohistochemical, ultrastructural and molecular analyses","volume":"59","author":"Lopez-Beltran","year":"2006","journal-title":"J Clin Pathol"},{"key":"R3-16-20240903","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/01.ju.0000129007.68711.b6","article-title":"Pediatric epithelioid sarcoma of the penis","volume":"172","author":"Lowentritt","year":"2004","journal-title":"J Urol"},{"key":"R4-16-20240903","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00005392-199907000-00041","article-title":"Primary extraskeletal Ewing's sarcoma of the external genitalia","volume":"162","author":"Toh","year":"1999","journal-title":"J Urol"},{"key":"R5-16-20240903","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.9738\/INTSURG-D-15-00010.1","article-title":"Peripheral primitive neuroectodermal tumor (pPNET) of the penis: A case report and literature review","volume":"100","author":"Huang","year":"2015","journal-title":"Int Surg"},{"key":"R6-16-20240903","first-page":"18650","article-title":"Primitive neuroectodermal tumor of the posterior urethral: A case report and literature review","volume":"9","author":"Hu","year":"2016","journal-title":"Int J Clin Exp Med"}],"container-title":["Indian Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/iju.IJU_178_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:14:25Z","timestamp":1787166865000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/iju.IJU_178_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/iju.iju_178_20","relation":{},"ISSN":["0970-1591"],"issn-type":[{"value":"0970-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}