{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:55:54Z","timestamp":1790776554418,"version":"4.1.0"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Staghorn stones are typically managed surgically due to their size, complexity, and infection risk. Uric acid stones are an exception. Prior reports of medical dissolution have been limited to small stones (&lt;20 mm). Here, we report a case in which large uric acid staghorn stones were successfully cleared with medical therapy. A 43-year-old male presented with bilateral uric acid staghorn calculi measuring 42 mm (27,155 mm\n                    <jats:sup>3<\/jats:sup>\n                    ) and 29 mm (11,562 mm\n                    <jats:sup>3<\/jats:sup>\n                    ) and obstructing left ureteral stones that required ureteroscopy. Treatment with febuxostat and potassium citrate resulted in dissolution of the staghorn stones after 15 weeks of therapy, on computed tomography imaging.\n                  <\/jats:p>","DOI":"10.4103\/iju.iju_331_26","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:00:33Z","timestamp":1790758833000},"page":"341-343","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral complete staghorn uric acid calculi successfully managed with oral chemolysis"],"prefix":"10.4103","volume":"42","author":[{"given":"Haresh","family":"Thummar","sequence":"first","affiliation":[{"name":"Department of Urology and Kidney Transplant, Zydus Hospital, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veda","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Department of Urology, Icahn School of Medicine at Mount Sinai, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mantu","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Urology, Icahn School of Medicine at Mount Sinai, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"R1-20260930","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1097\/01.ju.0000161171.67806.2a","article-title":"Chapter 1: AUA guideline on management of staghorn calculi: Diagnosis and treatment recommendations","volume":"173","author":"Preminger","year":"2005","journal-title":"J Urol"},{"key":"R3-20260930","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3390\/siuj5040047","article-title":"Oral dissolution therapy of uric acid stones: A systematic review","volume":"5","author":"Mousavi","year":"2024","journal-title":"Soc Int Urol J"},{"key":"R4-20260930","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.juro.2018.09.027","article-title":"Can we predict the outcome of oral dissolution therapy for radiolucent renal calculi? A prospective study","volume":"201","author":"Elsawy","year":"2019","journal-title":"J Urol"},{"key":"R5-20260930","doi-asserted-by":"crossref","first-page":"369","DOI":"10.4103\/UA.UA_20_19","article-title":"Oral dissolution therapy for renal radiolucent stones, outcome, and factors affecting response: A prospective study","volume":"11","author":"Salem","year":"2019","journal-title":"Urol Ann"}],"container-title":["Indian Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/iju.iju_331_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:02:05Z","timestamp":1790773325000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/iju.iju_331_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/iju.iju_331_26","relation":{},"ISSN":["0970-1591","1998-3824"],"issn-type":[{"value":"0970-1591","type":"print"},{"value":"1998-3824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]},"assertion":[{"value":"2026-05-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}