{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:55:51Z","timestamp":1790776551728,"version":"4.1.0"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Special AT-rich sequence-binding protein 2 (SATB2) expression in conjunction with CK20 expression has been established as a specific marker for the detection of colorectal adenocarcinomas. Recently, its expression in foregut, midgut, and hindgut neuroendocrine neoplasms has been documented. SATB2 expression has been documented in neuroendocrine neoplasms from various primary sites; however, its expression in the urinary bladder has not been reported. A case of primary small cell neuroendocrine carcinoma of the urinary bladder (SmCCB) is presented, where strong SATB2 expression led to the suspicion of metastatic neuroendocrine carcinomatous deposits from the lower gastrointestinal tract. However, on positron emission tomography\u2013computed tomography scan, no fluorodeoxyglucose-avid lesion elsewhere in the body was found, which established the diagnosis of primary SmCCB with SATB2 expression.<\/jats:p>","DOI":"10.4103\/iju.iju_354_26","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:00:15Z","timestamp":1790758815000},"page":"344-346","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Special AT-rich sequence-binding protein 2-positive primary small cell neuroendocrine carcinoma of the urinary bladder: A diagnostic pitfall"],"prefix":"10.4103","volume":"42","author":[{"given":"Ankita","family":"Soni","sequence":"first","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aminder","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"R1-20260930","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/ajmg.a.38022","article-title":"SATB2-associated syndrome: Mechanisms, phenotype, and practical recommendations","volume":"173","author":"Zarate","year":"2017","journal-title":"Am J Med Genet A"},{"key":"R2-20260930","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1309\/AJCPWW2URZ9JKQJU","article-title":"The role of SATB2 as a diagnostic marker for tumors of colorectal origin: Results of a pathology-based clinical prospective study","volume":"141","author":"Dragomir","year":"2014","journal-title":"Am J Clin Pathol"},{"key":"R3-20260930","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.path.2013.06.003","article-title":"Immunohistochemistry in Gastroenterohepatopancreatobiliary epithelial neoplasia: Practical applications, pitfalls, and emerging markers","volume":"6","author":"Bellizzi","year":"2013","journal-title":"Surg Pathol Clin"},{"key":"R4-20260930","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.humpath.2018.05.005","article-title":"Small cell carcinoma of the urinary bladder: A clinicopathological and immunohistochemical analysis of 81 cases","volume":"79","author":"Wang","year":"2018","journal-title":"Hum Pathol"},{"key":"R5-20260930","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1365-2559.2004.01980.x","article-title":"Small cell carcinoma of the bladder: A contemporary clinicopathological study of 51 cases","volume":"46","author":"Abrahams","year":"2005","journal-title":"Histopathology"},{"key":"R6-20260930","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/his.13943","article-title":"SATB2 in neuroendocrine neoplasms: Strong expression is restricted to well-differentiated tumours of lower gastrointestinal tract origin and is most frequent in Merkel cell carcinoma among poorly differentiated carcinomas","volume":"76","author":"Bellizzi","year":"2020","journal-title":"Histopathology"}],"container-title":["Indian Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/iju.iju_354_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:02:10Z","timestamp":1790773330000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/iju.iju_354_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/iju.iju_354_26","relation":{},"ISSN":["0970-1591","1998-3824"],"issn-type":[{"value":"0970-1591","type":"print"},{"value":"1998-3824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]},"assertion":[{"value":"2026-06-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}