{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:19:28Z","timestamp":1787775568122,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Our aim is to evaluate the clinical efficiency and safety of 60W Thulium fiber laser (TFL) during retrograde intrarenal surgery (RIRS). The performance of the TFL across different ranges of stone volumes and stone densities is assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Between October 2019 and August 2020, a prospective study was done on 135 patients with &lt; 20 mm renal stones, who underwent RIRS using TFL. Stone parameters, total laser time, total energy delivered (kJ), and fiber burn-back were recorded. Laser efficacy (J\/mm\n                      <jats:sup>3<\/jats:sup>\n                      ) and ablation speed (mm\n                      <jats:sup>3<\/jats:sup>\n                      \/s) were calculated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Data of 126 of 135 patients included in the study were analyzed. The mean patient age was 45.04 \u00b1 12.30 years. Mean stone size was 15.19 \u00b1 4.52 mm, and mean stone volume was 1061.85 \u00b1 806.81 mm\n                      <jats:sup>3<\/jats:sup>\n                      . Mean laser time was 19.78 \u00b1 12.32 min. At higher stone volume (&gt;1000 mm\n                      <jats:sup>3<\/jats:sup>\n                      ), J\/mm\n                      <jats:sup>3<\/jats:sup>\n                      decreased significantly from 16.18 \u00b1 5.90 to 10.92 \u00b1 3.21 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) and the ablation speed increased significantly (0.77 \u00b1 0.28\u20131.04 \u00b1 0.28 mm\n                      <jats:sup>3<\/jats:sup>\n                      \/s [\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001]). Stone density did not have a significant influence on the laser efficacy [B = -0.31 (-2.45 to 1.82, p=0.771)] or on the ablation speed [B = -0.06 (-0.17 to 0.05, p=0.278)]. Overall SFR was 93.6%. The complication rate was 16.6% (21\/126). Out of the 21, 12 patients had hematuria and 9 had fever, which were of Clavien grades 1\u20132.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Superpulse TFL is efficient and safe. The work efficiency increases for larger volume stones. The work efficiency remains the same across different stone densities. No complication more than Clavien grade 2 was encountered.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/iju.iju_60_22","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T03:12:03Z","timestamp":1689563523000},"page":"191-196","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["The clinical efficiency and safety of 60W superpulse thulium fiber laser in retrograde intrarenal surgery"],"prefix":"10.4103","volume":"38","author":[{"given":"Chandra Mohan","family":"Vaddi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paidakula","family":"Ramakrishna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soundarya","family":"Ganeshan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddalinga","family":"Swamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemnath","family":"Anandan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manas","family":"Babu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Panda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-5-20240903","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.eururo.2016.03.035","article-title":"Current standard technique for modern flexible ureteroscopy: Tips and tricks","volume":"70","author":"Giusti","year":"2016","journal-title":"Eur Urol"},{"key":"R3-5-20240903","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.juro.2007.10.083","article-title":"Flexible ureteroscopy and laser lithotripsy for single intrarenal stones 2 cm or greater-is this the new frontier?","volume":"179","author":"Breda","year":"2008","journal-title":"J Urol"},{"key":"R4-5-20240903","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/S0090-4295(99)80113-7","article-title":"Holmium: Yttrium-aluminum-garnet laser for endoscopic lithotripsy","volume":"45","author":"Matsuoka","year":"1995","journal-title":"Urology"},{"key":"R5-5-20240903","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/s41585-018-0035-8","article-title":"Advances in laser technology and fibre-optic delivery systems in lithotripsy","volume":"15","author":"Fried","year":"2018","journal-title":"Nat Rev Urol"},{"key":"R6-5-20240903","doi-asserted-by":"crossref","first-page":"S398","DOI":"10.21037\/tau.2019.08.01","article-title":"The laser of the future: Reality and expectations about the new thulium fiber laser \u2013 A systematic review","volume":"8","author":"Kronenberg","year":"2019","journal-title":"Transl Androl Urol"},{"key":"R7-5-20240903","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/lsm.23057","article-title":"High power holmium: YAG versus thulium fiber laser treatment of kidney stones in dusting mode: Ablation rate and fragment size studies","volume":"51","author":"Hardy","year":"2019","journal-title":"Lasers Surg Med"},{"key":"R8-5-20240903","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s00345-019-02785-9","article-title":"Preclinical comparison of superpulse thulium fiber laser and a holmium: YAG laser for lithotripsy","volume":"38","author":"Andreeva","year":"2020","journal-title":"World J Urol"},{"key":"R9-5-20240903","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1007\/s00345-020-03186-z","article-title":"Comparison of the ablation rates, fissures and fragments produced with 150 \u03bcm and 272 \u03bcm laser fibers with superpulsed thulium fiber laser: An in vitro study","volume":"39","author":"Panthier","year":"2021","journal-title":"World J Urol"},{"key":"R10-5-20240903","first-page":"e28","article-title":"MP03-20 dusting efficiency comparison between Moses technology of Ho: YAG laser and superpulse thulium fiber laser","volume":"201","author":"De Coninck","year":"2019","journal-title":"J Urol"},{"key":"R11-5-20240903","doi-asserted-by":"crossref","first-page":"e501","DOI":"10.1016\/S1569-9056(19)30373-2","article-title":"Comparing short, long, and Moses regimes of Ho: YAG laser vs. Super Pulse\u2122 fiber laser in vitro: Ablation speed and retropulsion effect","volume":"18","author":"Traxer","year":"2019","journal-title":"Eur Urol Suppl"},{"key":"R12-5-20240903","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00345-020-03178-z","article-title":"What is the exact definition of stone dust? 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