{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:30:58Z","timestamp":1786728658301,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Alcohol use is a major public health concern in India. Disulfiram is one of the few effective drugs approved for treatment of alcohol use disorder. There have been a few, if any, research studies on resistance to disulfiram as well as other nondeterrent effects of the drug. Here, we shall discuss three cases with disulfiram resistance, with one of them having possible anticraving effect, and also reflect on probable etiologies leading to this unexpected phenomenon. In this context, more research is needed into how different populations and ethnic\/racial groups respond to this medication.<\/jats:p>","DOI":"10.4103\/ipj.ipj_156_25","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T08:00:15Z","timestamp":1768896015000},"page":"158-160","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Disulfiram resistance in alcohol dependence: Myth or reality?"],"prefix":"10.4103","volume":"35","author":[{"given":"Prateek","family":"Rajput","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Vibhuh Clinic, Charoda B.M.Y, Durg, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anshumi","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, SBR Clinic, Risali, Durg, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"R1-20260120","article-title":"Magnitude of Substance Use in India 2019. 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A review of the alcohol-disulfiram reaction in practice","volume":"144","author":"Brewer","year":"1984","journal-title":"Br J Psychiatry"},{"key":"R10-20260120","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.biopsych.2012.07.011","article-title":"Pharmacogenetic randomized trial for cocaine abuse: Disulfiram and dopamine \u03b2-hydroxylase","volume":"73","author":"Kosten","year":"2013","journal-title":"Biol Psychiatry"}],"container-title":["Industrial Psychiatry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ipj.ipj_156_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:30:01Z","timestamp":1786725001000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ipj.ipj_156_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ipj.ipj_156_25","relation":{},"ISSN":["0972-6748","0976-2795"],"issn-type":[{"value":"0972-6748","type":"print"},{"value":"0976-2795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-05-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}