{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:33:52Z","timestamp":1787762032462,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This text discusses a case report of an affected person with bipolar ailment who developed the syndrome of irreversible lithium effectuated neurotoxicity (SILENT). In this case of a 62-year-old man with bipolar affective disorder, we found how continual lithium therapy can position a patient requiring chronic mood stabilizer treatment vulnerable to developing the silent syndrome. The case presentation covered a set of symptoms inclusive of encephalopathy, cerebellar dysfunction, stress, and limb tremors at the time of admission. A serial neurological examination and mental status examination for ascertaining the diagnosis of the silent syndrome were carried out, and the affected person was advised to discontinue lithium and was handled symptomatically for other symptoms. We ought to identify and manage the hazard elements contributing to the development of this syndrome.<\/jats:p>","DOI":"10.4103\/ipj.ipj_189_22","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T15:03:24Z","timestamp":1688396604000},"page":"445-447","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["\u201cSILENT\u201d: A case report of a rare syndromal presentation of chronic lithium toxicity"],"prefix":"10.4103","volume":"32","author":[{"given":"Bhanu","family":"Dahiya","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Yenepoya Medical College and Hospital, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashwath Sathyanath","family":"Mutathodi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Yenepoya Medical College and Hospital, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Kakunje","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Yenepoya Medical College and Hospital, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4103\/0019-5545.196974","article-title":"Clinical practice guidelines for the management of the bipolar disorder","volume":"59","author":"Shah","year":"2017","journal-title":"Indian J Psychiatry"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.jns.2008.10.010","article-title":"The syndrome of irreversible lithium-effectuated neurotoxicity (SILENT):One-year follow-up of a single case","volume":"277","author":"Porto","year":"2009","journal-title":"J Neurol Sci"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1136\/jnnp.50.9.1246","article-title":"The syndrome of irreversible lithium effectuated neurotoxicity","volume":"50","author":"Adityanjee","year":"1987","journal-title":"Neurol Neurosurg Psychiatry"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/01.wnf.0000150871.52253.b7","article-title":"The syndrome of irreversible Lithium-e effectuated neurotoxicity","volume":"28","author":"Adityanjee","year":"2005","journal-title":"Clin Neuropharmacol"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/mds.21318","article-title":"Permanent lithium-induced cerebellar toxicity:Three cases and review of literature","volume":"22","author":"Niethammer","year":"2007","journal-title":"Mov Disord"}],"container-title":["Industrial Psychiatry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ipj.ipj_189_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:10:41Z","timestamp":1787760641000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ipj.ipj_189_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,28]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ipj.ipj_189_22","relation":{},"ISSN":["0972-6748","0976-2795"],"issn-type":[{"value":"0972-6748","type":"print"},{"value":"0976-2795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,28]]},"assertion":[{"value":"2022-10-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}