{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:37:27Z","timestamp":1787071047569,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Kidney donation is a significant procedure that can profoundly impact the emotional, psychological, and social well-being of renal donors. However, there is a lack of sufficient evidence regarding the specific effects of donation on the mental health and quality of life (QOL) of living kidney donors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate and compare the levels of depression, anxiety, and QOL among living kidney donors before and after the donation procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>We conducted a prospective longitudinal cohort study involving 50 consecutive living renal donors, assessing them before and 3 months after kidney donation. Depression and anxiety were evaluated using the Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Depression Rating Scale (HAM-D), respectively. Furthermore, the QOL of kidney donors was compared using the World Health Organization Quality of Life Brief Version (WHOQOL-BREF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result:<\/jats:title>\n                    <jats:p>\n                      The average age of kidney donors was 40.86 \u00b1 8.59 years. Pre-transplant HAM-D and HAM-A scores showed significant negative correlations with post-transplant QoL domains (**\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Regression analysis highlighted pre-transplant HAM-D as a significant predictor of post-transplant depression (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.013).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Statistically significant differences in pre- and post-donation HAM-D and HAM-A scores were found, but clinical significance is crucial for interpreting real-world implications. Renal transplantation did not worsen mental health or QOL for donors post transplant, highlighting the importance of addressing pre-transplant depression and anxiety. Further research is needed to assess clinical significance and integrate mental health considerations into transplant care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ipj.ipj_241_24","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T10:05:19Z","timestamp":1734516319000},"page":"334-340","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Depression, anxiety, and quality of life among kidney donors before and after the kidney donation: A prospective study from a tertiary care center in India"],"prefix":"10.4103","volume":"33","author":[{"given":"Geetika","family":"Chopra","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Mahatma Gandhi Medical College, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Gaur","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, JNUIMSRC, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,17]]},"reference":[{"key":"R2-20260424","first-page":"180.","article-title":"Psychological Aspects of Kidney Transplantation","volume":"171","author":"Trzcinska","year":"2011","journal-title":"After the Kidney Transplant\u2013The Patients and Their Allograft"},{"key":"R3-20260424","doi-asserted-by":"crossref","first-page":"321.","DOI":"10.4103\/0971-4065.165006","article-title":"Evaluation of psychiatric issues in renal transplant setting","volume":"25","author":"Naqvi","year":"2015","journal-title":"Indian J Nephrol"},{"key":"R4-20260424","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1053\/j.ajkd.2011.11.043","article-title":"The motivations and experiences of living kidney donors: A thematic synthesis","volume":"60","author":"Tong","year":"2012","journal-title":"Am J Kidney 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