{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:32:26Z","timestamp":1789014746838,"version":"build-2803163510"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["INSJ"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Degenerative cervical radiculopathy results from nerve root compression in the cervical neural foramina, often due to a herniated disc, osteophyte, or facetal\/ligamentum flavum hypertrophy. Typically, 80% of patients show improvement within the initial 12 weeks through nonoperative measures, with surgical intervention considered for non-responders. This study aimed to compare clinical and radiological outcomes in cervical radiculopathy patients undergoing prolonged conservative care, anterior cervical discectomy and fusion (ACDF), or anterior cervical disc replacement (ACDR) after a 1\u2010year follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Our study was a retrospective single\u2010center study involving 780 cervical radiculopathy patients from January 2012 to December 2021. About 80.12% found relief with conservative management within 12 weeks. Remaining 155 patients were offered surgery, with 73 opting for continued conservative care, and 82 undergoing surgery (55 with ACDF and 27 with ACDR). Evaluation was done using visual analogue scale (VAS), Neck Disability Index (NDI), and radiographic parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean follow\u2010up was 11.58\u2009\u00b1\u20096.7 months. ACDR group: Mean age 43.38\u2009\u00b1\u20098.56, VAS 7.81\u2009\u00b1\u20091.04 preoperatively, improved significantly to 2.07\u2009\u00b1\u20091.34 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) at 1\u2010year follow\u2010up. ACDF group: Mean age 44.85\u2009\u00b1\u200910.65, VAS 8.22\u2009\u00b1\u20091.21 preoperatively, improved significantly to 2.09\u2009\u00b1\u20091.01 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) at 1\u2010year follow\u2010up. Conservative group: Mean age 45.04\u2009\u00b1\u200911.19, VAS 7.77\u2009\u00b1\u20091.86 preoperatively, improved significantly to 2.08\u2009\u00b1\u20091.40 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) at 1\u2010year follow\u2010up. Radiographic parameters significantly improved in all groups at 1\u2010year follow\u2010up (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Range of motion (ROM) changes varied across groups. Miyazaki\u2019s grading and Kim\u2019s score showed comparable results.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Comparable clinical and radiological outcomes were observed among conservative, ACDF, and ACDR approaches. ACDR approach demonstrated a better NDI score outcome. Neck ROM was better maintained or improved in the ACDR approach, decreased in ACDF, and remained almost similar in the conservative group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/isj.isj_60_23","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T02:01:37Z","timestamp":1707357697000},"page":"87-93","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Management outcomes of cervical radiculopathy with conservative treatment, anterior cervical discectomy fusion (ACDF), and anterior cervical disc replacement (ACDR)\u2014Retrospective single center matched cohort study"],"prefix":"10.4103","volume":"7","author":[{"given":"Saumyajit","family":"Basu","sequence":"first","affiliation":[{"name":"Department of Spine Surgery, Kothari Medical Centre, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piyush","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Kothari Medical Centre, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Hanasoge","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Kothari Medical Centre, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya V","family":"Guduru","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Kothari Medical Centre, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piyush W","family":"Gadegone","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Kothari Medical Centre, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitul","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Kothari Medical Centre, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"CIT0001-20240903","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1007\/s00586-009-1017-6","article-title":"Intermediate clinical and radiological results of cervical TDR (Mobi-C) with up to 2 years of follow-up","volume":"18","author":"Beaurain","year":"2009","journal-title":"Eur Spine J"},{"key":"CIT0002-20240903","first-page":"69","article-title":"The pathogenesis of cervical spondylosis","author":"Lestini","year":"1989","journal-title":"Clin Orthop Relat Res"},{"key":"CIT0003-20240903","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/00007632-199903150-00021","article-title":"Outcome in patients with cervical radiculopathy. 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