{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:09Z","timestamp":1786728429736,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:p>\n                    Plants from the Myrtaceae and Lamiaceae families, such as\n                    <jats:italic toggle=\"yes\">Melaleuca leucadendron<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Pogostemon cablin<\/jats:italic>\n                    , are known to be used as essential oils. This study aimed to determine the antioxidant and antiaging activity of the methanol extract of leaves of\n                    <jats:italic toggle=\"yes\">Melaleuca leucadendron<\/jats:italic>\n                    (MEML) and\n                    <jats:italic toggle=\"yes\">P. cablin<\/jats:italic>\n                    (MEPC). Antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, and antiaging activity was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method. The results of this study showed that each of the MEML and MEPC extracts had a yield of 55.95% and 21.24% and contained alkaloid, flavonoid, saponin, terpenoid, steroid, and phenolic compounds. The results of the antioxidant test showed that MEML and MEPC extracts had a very strong category with IC\n                    <jats:sub>50<\/jats:sub>\n                    values of 3.23 \u00b5g\/mL and 47.60 \u00b5g\/mL, respectively. Antiaging activity was shown in the cell viability of MEPC with concentrations of 20 \u00b5g\/mL (106.879%), 50 \u00b5g\/mL (95%), 100 \u00b5g\/mL (85.434%), and 200 \u00b5g\/mL (35.665%), and MEML with concentrations of 20 \u00b5g\/mL (108.237%), 50 \u00b5g\/mL (106.445%), 100 \u00b5g\/mL (88.006%), and 200 \u00b5g\/mL (79.451%).\n                  <\/jats:p>","DOI":"10.4103\/japtr.japtr_239_25","type":"journal-article","created":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T16:00:36Z","timestamp":1778342436000},"page":"115-120","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparative study of antioxidant and antiaging activities of methanol extract from eucalyptus (Melaleuca leucadendron) and patchouli (Pogostemon cablin) leaves"],"prefix":"10.4103","volume":"17","author":[{"given":"Maulidna","family":"Ginting","sequence":"first","affiliation":[{"name":"Department of Chemical Engineering, Politeknik Teknologi Kimia Industri, Padang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Novia","family":"Delza","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Politeknik ATI Padang, Padang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. Zaid Thariq","family":"Gunana","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia"},{"name":"Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Universitas Syiah Kuala, Banda Aceh, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elly","family":"Sufriadi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binawati","family":"Ginting","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chyntia","family":"Audhina","sequence":"additional","affiliation":[{"name":"Department 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