{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:25:27Z","timestamp":1787757927546,"version":"build-2784847793"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>Saliva is a multilayered secretion. The quality of saliva is just as crucial as the quantity. Saliva is necessary for preserving the integrity of oral structures, personal connections, digestion, and acid\u2013base balance. The acid\u2013base balance in one's oral environment is always being challenged. It happens every time we eat a meal, and when microorganisms are present. At a pH of 5 or 5.5, the demineralization of the enamel and hard tooth structures occurs. This study aimed to raise awareness about the importance of acid\u2013base balance of saliva in dental health. A self-structured questionnaire was prepared to assess the awareness on the importance of acid\u2013base balance in maintaining oral health. The questionnaire consisted of 20 questions, and the results were plotted in a graph. The Chi-square test was employed for evaluating the data, which was done with SPSS software. The study indicated that 91.74% of the participants were aware of the salivary pH in case of healthy gingiva, 34.82% of the respondents were aware of the salivary pH in case of chronic gingivitis, and 20.33% of the respondents were aware of the salivary pH in case of chronic periodontitis. We also correlated our results with gender and year of study. Oral health plays a major role in identifying systemic diseases and hence enough knowledge about various aspects about the oral cavity and its manifestations needs to be created among dental students to ensure that they become efficient dental surgeons in the future. Even though a fair amount of people knew the pH of clinically healthy gingiva, most of them did not know the pH at which periodontitis or gingivitis was caused. Hence, creating awareness about this topic stands vital. Further studies are required for a better understanding of salivary components and how they affect the caries process. The utilization of modified oral molecules as medicinal agents could become a reality with this understanding. Our findings imply that being aware of dietary composition has an impact on acid\u2013base balance. To maintain the correct acid\u2013base balance, more awareness of protein consumption is required.<\/jats:p>","DOI":"10.4103\/japtr.japtr_402_22","type":"journal-article","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T11:41:46Z","timestamp":1716810106000},"page":"S325-S329","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Awareness about the significance of acid\u2013base balance of saliva in maintaining oral health"],"prefix":"10.4103","volume":"13","author":[{"given":"Charanya","family":"Suresh","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishnupriya","family":"Veeraraghavan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selvaraj","family":"Jayaraman","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Gayathri","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kavitha","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"R1-20260225","doi-asserted-by":"crossref","first-page":"100322.","DOI":"10.1016\/j.jctube.2022.100322","article-title":"Assessing physical and chemical properties of saliva among tuberculosis patients on anti-tuberculosis treatment \u2013 An observational study","volume":"28","author":"Gowdappa Doddawad","year":"2022","journal-title":"J Clin Tuberc Other Mycobact Dis"},{"key":"R2-20260225","first-page":"C34","article-title":"Influence of hypertension on pH of saliva and flow rate in elder adults correlating with oral health status","volume":"10","author":"Nimma","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"R3-20260225","doi-asserted-by":"crossref","first-page":"2174.","DOI":"10.3390\/nu14102174","article-title":"On the pathogenicity of the oral biofilm: A critical review from a biological, evolutionary, and nutritional point of view","volume":"14","author":"Woelber","year":"2022","journal-title":"Nutrients"},{"key":"R4-20260225","doi-asserted-by":"crossref","first-page":"70","DOI":"10.33615\/jkohs.2019.7.3.70","article-title":"The relation of amount of the saliva secretion rate and saliva pH on taking 2 liters of water per a day","volume":"7","author":"Kim","year":"2019","journal-title":"Korean Soc Oral Health Sci"},{"key":"R5-20260225","first-page":"1","article-title":"A comprehensive and critical review on ethnopharmacological importance of desert Truffles: Terfezia claveryi, Terfezia boudieri, and Tirmania nivea","volume":"37","author":"Veeraraghavan","year":"2021","journal-title":"Food Rev Int"},{"key":"R6-20260225","first-page":"100333.","article-title":"An in vitro study on hexavalent chromium [Cr (VI)] remediation using iron oxide nanoparticles based beads","volume":"14","author":"Sathya","year":"2020","journal-title":"Environ Nanotechnol Monit Manag"},{"key":"R7-20260225","doi-asserted-by":"crossref","first-page":"5501","DOI":"10.1016\/j.arabjc.2020.03.028","article-title":"Piperine loaded zinc oxide nanocomposite inhibits the PI3K\/AKT\/mTOR signaling pathway via attenuating the development of gastric carcinoma: In vitro and in-vivo studies","volume":"13","author":"Yang","year":"2020","journal-title":"Arab J Chem"},{"key":"R8-20260225","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1080\/10408398.2020.1837725","article-title":"Consumption of reused vegetable oil intensifies BRCA1 mutations","volume":"62","author":"Rajendran","year":"2022","journal-title":"Crit Rev Food Sci Nutr"},{"key":"R9-20260225","doi-asserted-by":"crossref","first-page":"105132.","DOI":"10.1016\/j.archoralbio.2021.105132","article-title":"Inhibition of Streptococcus mutans, antioxidant property and cytotoxicity of novel nano-zinc oxide varnish","volume":"126","author":"Barma","year":"2021","journal-title":"Arch Oral Biol"},{"key":"R10-20260225","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/ipd.12662","article-title":"Can 5-year-olds sensibly self-report the impact of developmental enamel defects on their quality of life?","volume":"31","author":"Samuel","year":"2021","journal-title":"Int J Paediatr Dent"},{"key":"R11-20260225","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/ipd.12757","article-title":"Dental pain, parental SARS-CoV-2 fear and distress on quality of life of 2 to 6 year-old children during COVID-19","volume":"31","author":"Samuel","year":"2021","journal-title":"Int J Paediatr Dent"},{"key":"R12-20260225","doi-asserted-by":"crossref","first-page":"111656.","DOI":"10.1016\/j.msec.2020.111656","article-title":"Osteogenic differentiation and mineralization potential of zine oxide nanoparticles from Scutellaria baicalensis on human osteoblast-like MG-63 cells","volume":"119","author":"Tang","year":"2021","journal-title":"Mater Sci Eng C"},{"key":"R13-20260225","doi-asserted-by":"crossref","first-page":"3633","DOI":"10.1016\/j.sjbs.2021.05.007","article-title":"Green synthesis of silver nanoparticles from aqueous extract of Scutellaria barbata and coating on the cotton fabric for antimicrobial applications and wound healing activity in fibroblast cells (L929)","volume":"28","author":"Veeraraghavan","year":"2021","journal-title":"Saudi J Biol Sci"},{"key":"R14-20260225","doi-asserted-by":"crossref","first-page":"3641","DOI":"10.1016\/j.sjbs.2021.05.006","article-title":"Rhaponticin suppresses osteosarcoma through the inhibition of PI3K-Akt-mTOR pathway","volume":"28","author":"Mickymaray","year":"2021","journal-title":"Saudi J Biol Sci"},{"key":"R15-20260225","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.jds.2020.02.009","article-title":"Is a filled lateral canal \u2013 A sign of superiority?","volume":"15","author":"Teja","year":"2020","journal-title":"J Dent Sci"},{"key":"R16-20260225","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1038\/s41423-020-0383-1","article-title":"Innate lymphoid cells: Potent early mediators of the host immune response during sepsis","volume":"17","author":"Theertha","year":"2020","journal-title":"Cell Mol Immunol"},{"key":"R17-20260225","doi-asserted-by":"crossref","first-page":"104648.","DOI":"10.1016\/j.archoralbio.2020.104648","article-title":"Caries and periodontitis associated bacteria are more abundant in human saliva compared to other great apes","volume":"111","author":"Boehlke","year":"2020","journal-title":"Arch Oral Biol"},{"key":"R18-20260225","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0899-9007(03)00062-5","article-title":"Nutrition, saliva, and oral health","volume":"19","author":"Lingstr\u00f6m","year":"2003","journal-title":"Nutrition"},{"key":"R19-20260225","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/jtxs.12356","article-title":"Aging-related changes in quantity and quality of saliva: Where do we stand in our understanding?","volume":"50","author":"Xu","year":"2019","journal-title":"Journal of Texture Studies"},{"key":"R20-20260225","first-page":"303","article-title":"Saliva between normal and pathological. Important factors in determining systemic and oral health","volume":"2","author":"Iorgulescu","year":"2009","journal-title":"J Med Life"},{"key":"R21-20260225","doi-asserted-by":"crossref","first-page":"656926.","DOI":"10.3389\/fmed.2021.656926","article-title":"Oral mucosa, saliva, and COVID-19 infection in oral health care","volume":"8","author":"Atukorallaya","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"R22-20260225","doi-asserted-by":"crossref","first-page":"8.","DOI":"10.4103\/jpcdoh.jpcdoh_9_20","article-title":"Biomarkers in saliva as diagnostic tool in early diagnosis of oral submucous fibrosis","volume":"2","author":"Mandal","year":"2021","journal-title":"J Prim Care Dent Oral Health"},{"key":"R23-20260225","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0003-9969(89)90007-1","article-title":"Influence of flow rate, pH and plasma fluoride concentrations on fluoride concentration in human parotid saliva","volume":"34","author":"Oliveby","year":"1989","journal-title":"Arch Oral Biol"}],"container-title":["Journal of Advanced Pharmaceutical Technology &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/japtr.japtr_402_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:59:32Z","timestamp":1787756372000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/japtr.japtr_402_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":23,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/japtr.japtr_402_22","relation":{},"ISSN":["2231-4040","0976-2094"],"issn-type":[{"value":"2231-4040","type":"print"},{"value":"0976-2094","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"2022-05-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}