{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:23:12Z","timestamp":1787746992205,"version":"build-2784847793"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    Vitamin K1 intake is an important modifiable factor in dietary counseling for warfarin patients; however, region-specific food composition data in Thailand are limited. This small compositional pilot study aimed to determine Vitamin K1 concentrations in five commonly consumed indigenous vegetables from Upper Northern Thailand and to summarize estimated Vitamin K1 intake under predefined portion-size scenarios. Fresh vegetable samples were collected from local markets in Phayao Province and analyzed by the high-performance liquid chromatography with fluorescence detection. Estimated Vitamin K1 intake was modeled for three consumption scenarios (100, 300, and 1200 g\/day) and compared to a benchmark intake of 150 \u03bcg\/day from the literature. The concentration of Vitamin K1 ranged from 71.3 to 212.5 \u03bcg\/100 g fresh weight, with\n                    <jats:italic toggle=\"yes\">Gymnema inodorum<\/jats:italic>\n                    having the highest concentration. The 100 and 300 g\/day scenarios were used as primary descriptive scenarios, whereas the 1200 g\/day scenario was retained only as a conservative sensitivity analysis. These findings should be interpreted as descriptive intake estimates relevant to dietary counseling and not as evidence of altered anticoagulation outcomes. Data on the Vitamin K1 composition of different regions may help to provide more locally adapted dietary advice for patients taking warfarin.\n                  <\/jats:p>","DOI":"10.4103\/japtr.japtr_42_26","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:00:09Z","timestamp":1786546809000},"page":"208-212","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Vitamin K1 in indigenous vegetables from upper northern Thailand: High-performance liquid chromatography measurement and scenario-based intake assessment relevant to warfarin dietary counseling"],"prefix":"10.4103","volume":"17","author":[{"given":"Chumaphorn","family":"Rodseeda","sequence":"first","affiliation":[{"name":"Department of Occupational Health and Safety, School of Public Health, Phayao, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nakit","family":"Chansamut","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, University of Phayao, Phayao, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"R1-20260826","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0083-6729(07)00012-X","article-title":"Warfarin therapy: Influence of pharmacogenetic and environmental factors on the anticoagulant response to warfarin","volume":"78","author":"Siguret","year":"2008","journal-title":"Vitam Horm"},{"key":"R2-20260826","first-page":"389","article-title":"Compilation of a provisional UK database for the phylloquinone (vitamin K1) content of foods","volume":"83","author":"Bolton-Smith","year":"2000","journal-title":"Br J Nutr"},{"key":"R3-20260826","doi-asserted-by":"crossref","first-page":"4851","DOI":"10.52711\/0974-360X.2022.00815","article-title":"Influence of vitamin K intake on INR and anticoagulation in outpatients taking warfarin","volume":"15","author":"Putriana","year":"2022","journal-title":"Res J Pharm Technol"},{"key":"R4-20260826","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/j.1753-4887.1999.tb01815.x","article-title":"Vitamin K: A practical guide to the dietary management of patients on warfarin","volume":"57","author":"Booth","year":"1999","journal-title":"Nutr Rev"},{"key":"R5-20260826","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.3390\/foods9121748","article-title":"Nutrient and mineral compositions of wild leafy vegetables of the Karen and Lawa communities in Thailand","volume":"9","author":"Punchay","year":"2020","journal-title":"Foods"},{"key":"R6-20260826","doi-asserted-by":"crossref","first-page":"120","DOI":"10.3390\/d15010120","article-title":"Very high food plant diversity among ethnic groups in Northern Thailand","volume":"15","author":"Panyadee","year":"2023","journal-title":"Diversity"},{"key":"R8-20260826","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1182\/blood-2004-04-1525","article-title":"Effect of Vitamin K intake on the stability of oral anticoagulant treatment: Dose-response relationships in healthy subjects","volume":"104","author":"Schurgers","year":"2004","journal-title":"Blood"},{"key":"R9-20260826","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1365-2125.2010.03672.x","article-title":"Warfarin and Vitamin K intake in the era of pharmacogenetics","volume":"70","author":"Lurie","year":"2010","journal-title":"Br J Clin Pharmacol"},{"key":"R11-20260826","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1160\/TH04-12-0773","article-title":"Patients with unstable control have a poorer dietary intake of Vitamin K compared to patients with stable control of anticoagulation","volume":"93","author":"Sconce","year":"2005","journal-title":"Thromb Haemost"},{"key":"R12-20260826","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1365-2141.2010.08537.x","article-title":"High usual dietary Vitamin K intake is associated with low relative variability in Vitamin K intake: Implications for anticoagulant therapy","volume":"153","author":"Presse","year":"2011","journal-title":"Br J Haematol"},{"key":"R14-20260826","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jfca.2004.07.004","article-title":"Phylloquinone (Vitamin K1) content of vegetables","volume":"18","author":"Damon","year":"2005","journal-title":"J Food Compos Anal"},{"key":"R15-20260826","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4103\/JAPTR.JAPTR_156_24","article-title":"Analysis of Vitamin K1 levels in several types of vegetables consumed by warfarin-used patients","volume":"16","author":"Putriana","year":"2025","journal-title":"J Adv Pharm Technol Res"},{"key":"R18-20260826","doi-asserted-by":"crossref","first-page":"4420","DOI":"10.3390\/molecules29184420","article-title":"Quantitative study of Vitamin K in plants by pressurized liquid extraction and LC-MS\/MS","volume":"29","author":"Bryshten","year":"2024","journal-title":"Molecules"},{"key":"R19-20260826","doi-asserted-by":"crossref","first-page":"e15197","DOI":"10.1590\/s2175-97902017000215197","article-title":"Vitamin K: Content in food consumed in S\u00e3o Paulo, Brazil","volume":"53","author":"Faria","year":"2017","journal-title":"Braz J Pharm Sci"}],"container-title":["Journal of Advanced Pharmaceutical Technology &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/JAPTR.JAPTR_42_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:00:48Z","timestamp":1787745648000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/JAPTR.JAPTR_42_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/japtr.japtr_42_26","relation":{},"ISSN":["2231-4040","0976-2094"],"issn-type":[{"value":"2231-4040","type":"print"},{"value":"0976-2094","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-02-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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