{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:36:30Z","timestamp":1786739790040,"version":"build-2736575974"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Direct pulp capping (DPC) preserves pulp vitality and stimulates reparative dentin formation. Photobiomodulation therapy (PBMT) may enhance healing especially with platelet-rich fibrin (PRF) and mineral trioxide aggregate (MTA). This study aims to assess the effects of PBMT, alone or with PRF or MTA, on postoperative pain after DPC and on dentin bridge thickness using cone-beam computed tomography (CBCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Sixty patients (17\u201345 years) with reversible pulpitis in permanent molars were randomly divided into three groups (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 20 each): Group A: MTA with PBMT (A\n                      <jats:sub>1<\/jats:sub>\n                      ) and without PBMT (A\n                      <jats:sub>2<\/jats:sub>\n                      ), Group B: PRF with PBMT (B\n                      <jats:sub>1<\/jats:sub>\n                      ) and without PBMT (B\n                      <jats:sub>2<\/jats:sub>\n                      ), and Group C: only PBMT. Clinical and radiographic follow-up was done at 3, 6, and 12 months. The thickness of the dentin bridge was measured at all the intervals using CBCT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At 24 h, there was no significant reduction in pain compared to baseline across all the groups. However, in the first and second weeks, groups treated with PBMT showed a significant reduction in pain (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.00). CBCT revealed that PBMT-treated groups had greater dentin bridge development, particularly in Group B\n                      <jats:sub>2<\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>PBMT with PRF was associated with better pain reduction and dentin bridge formation than other interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcde.jcde_174_26","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T17:07:51Z","timestamp":1780074471000},"page":"626-632","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of dentin bridge formation and postoperative pain reduction after direct pulp capping using photobiomodulation therapy, platelet-rich fibrin, and mineral trioxide aggregate \u2013 A randomized clinical trial"],"prefix":"10.4103","volume":"29","author":[{"given":"Rishika","family":"Mohanty","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Dash","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashirekha","family":"Govind","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,5,29]]},"reference":[{"issue":"Suppl 3","key":"R1-20260601","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/iej.13688","article-title":"Present status and future directions-vital pulp treatment and pulp preservation strategies","volume":"55","author":"Duncan","year":"2022","journal-title":"Int Endod J"},{"key":"R2-20260601","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4103\/0972-0707.212247","article-title":"A comparison of human dental pulp response to calcium hydroxide and biodentine as direct pulp-capping agents","volume":"20","author":"Jalan","year":"2017","journal-title":"J Conserv Dent"},{"key":"R3-20260601","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jdsr.2023.02.002","article-title":"Direct pulp capping procedures \u2013 Evidence and practice","volume":"59","author":"Islam","year":"2023","journal-title":"Jpn Dent 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