{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:30:26Z","timestamp":1787070626060,"version":"build-2736575974"},"reference-count":63,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Matrix metalloproteinases (MMPs) have been identified as agents that disintegrate the collagen structures of dental hybrid layers, resulting in reduced restorative bond strength. Multiple MMP inhibitors (MMPIs) are known to counteract this degenerative mechanism, thereby preserving bond strength and promoting the longevity of resin-based restorations. Additionally, literature suggests that certain MMPI materials possess antimicrobial\/anticariogenic properties, potentially reducing the risk of secondary caries development. Therefore, this review article aims to narrate on the integration of matrix metalloproteinase inhibitors into adhesive systems and their impact on bond strength.<\/jats:p>","DOI":"10.4103\/jcde.jcde_199_24","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T03:09:41Z","timestamp":1717643381000},"page":"566-571","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Matrix metalloproteinase inhibitors in restorative dentistry"],"prefix":"10.4103","volume":"27","author":[{"given":"I.","family":"Perarivalan","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janani","family":"Karunakaran","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathashri","family":"Anbalagan","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Harishma","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishnu","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"key":"R1-20240904","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s13191-012-0247-1","article-title":"Dental esthetics and its impact on psycho-social well-being and dental self confidence: A campus based survey of North Indian university students","volume":"13","author":"Afroz","year":"2013","journal-title":"J Indian Prosthodont Soc"},{"key":"R2-20240904","doi-asserted-by":"crossref","first-page":"3163904","DOI":"10.1155\/2016\/3163904","article-title":"Esthetic Concerns and Acceptability of Treatment Modalities in Primary Teeth: A Comparison between Children and Their Parents","volume":"2016","author":"Pani","year":"2016","journal-title":"Int J Dent"},{"key":"R3-20240904","first-page":"457","article-title":"Studies on dental self-curing resins(3). 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