{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:29:11Z","timestamp":1786649351644,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context:<\/jats:title>\n                    <jats:p>Gutta-percha (GP) gets contaminated during handling. It becomes imperative to ensure GP is sterile before placement in root canal space.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>\n                      The aim of the study was to evaluate and compare the tensile strength of GP treated with four different disinfectant solutions: 3% sodium hypochlorite (NaOCl), amla juice (AJ),\n                      <jats:italic toggle=\"yes\">Aloe vera<\/jats:italic>\n                      (AV) juice, and pancha tulsi (PT).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings and Design:<\/jats:title>\n                    <jats:p>\n                      The study design was an\n                      <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                      study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Fifty GP cones with a size of 30 were procured from sealed packages in five different groups. Experimental groups were disinfected for 1 min with 3% NaOCl, AJ, AV, and PT except the control group. Tensile and Brinell Testing Machine is used to measure the tensile strengths of GP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis Used:<\/jats:title>\n                    <jats:p>\n                      Results were subjected to statistical analysis using the Kruskal\u2013Wallis test followed by Dunn\u2019s\n                      <jats:italic toggle=\"yes\">post hoc<\/jats:italic>\n                      test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean tensile strength values for Groups A, B, C, D, and E are 9.49 Mpa, 13.33 Mpa, 12.58 Mpa, 12.69 MPa, and 13.56 MPa, respectively. In the herbal disinfectant group, such as AJ, AV, and PT, the tensile strength was not significantly altered, whereas in the 3% NaOCl group, it was reduced considerably.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>AJ, AV juice, and PT as a GP disinfectant do not alter the tensile strength of GP cones.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcde.jcde_300_23","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T02:01:05Z","timestamp":1707357665000},"page":"154-158","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Effect of various disinfectant solutions on the tensile strength of gutta-percha using the rapid sterilization technique"],"prefix":"10.4103","volume":"27","author":[{"given":"Sandeep","family":"Rudranaik","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoganatha Hanasoge","family":"Nagashetty","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahadev Chikmagarvalli Krishna","family":"Gowda","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharath Makonahalli","family":"Jaganath","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. B.","family":"Nirmala","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. C. Bharath","family":"Gowda","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2,8]]},"reference":[{"key":"R1-20240904","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1590\/S1678-77572009000300022","article-title":"Examination of gutta-percha cones for microbial contamination during chemical use","volume":"17","author":"Kayaoglu","year":"2009","journal-title":"J Appl Oral Sci"},{"key":"R2-20240904","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00784-009-0295-z","article-title":"Contamination of gutta-percha and Resilon cones taken directly from the manufacturer","volume":"14","author":"Seabra Pereira","year":"2010","journal-title":"Clin Oral Investig"},{"key":"R3-20240904","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0099-2399(75)80098-7","article-title":"Rapid sterilization of gutta-percha cones with 5.25% sodium hypochlorite","volume":"1","author":"Senia","year":"1975","journal-title":"J Endod"},{"key":"R4-20240904","doi-asserted-by":"crossref","first-page":"264","DOI":"10.5395\/rde.2017.42.4.264","article-title":"Evaluation of antimicrobial activity and efficacy of herbal oils and extracts in disinfection of gutta percha cones before obturation","volume":"42","author":"Makade","year":"2017","journal-title":"Restor Dent Endod"},{"key":"R5-20240904","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.tripleo.2004.10.002","article-title":"Disinfection of gutta-percha cones with chlorhexidine and sodium hypochlorite","volume":"100","author":"Gomes","year":"2005","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R6-20240904","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0099-2399(99)80290-8","article-title":"Rapid decontamination of gutta-percha cones with sodium hypochlorite","volume":"25","author":"Cardoso","year":"1999","journal-title":"J Endod"},{"key":"R7-20240904","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1046\/j.1365-2591.2001.00412.x","article-title":"Efficacy of chemical sterilization and storage conditions of gutta-percha cones","volume":"34","author":"da Motta","year":"2001","journal-title":"Int Endod J"},{"key":"R8-20240904","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4103\/JCD.JCD_505_20","article-title":"Evaluation of surface analysis of gutta-percha after disinfecting with sodium hypochlorite, silver nanoparticles, and chitosan nanoparticles by atomic force microscopy:An in vitro study","volume":"24","author":"Karunakar","year":"2021","journal-title":"J Conserv Dent"},{"key":"R9-20240904","doi-asserted-by":"crossref","first-page":"18","DOI":"10.4103\/0972-0707.124102","article-title":"A comparative evaluation of the effect of 5.25% sodium hypochlorite and 2% chlorhexidine on the surface texture of Gutta-percha and Resilon cones using atomic force microscope","volume":"17","author":"Tilakchand","year":"2014","journal-title":"J Conserv Dent"},{"key":"R10-20240904","doi-asserted-by":"crossref","first-page":"471","DOI":"10.4103\/0972-0707.168813","article-title":"Comparative evaluation of tensile strength of gutta-percha cones with a herbal disinfectant","volume":"18","author":"Mahali","year":"2015","journal-title":"J Conserv Dent"},{"key":"R11-20240904","doi-asserted-by":"crossref","first-page":"169","DOI":"10.25130\/tjds.2.2.13","article-title":"Effect of different disinfectant solutions on the properties of gutta-percha cones","volume":"2","author":"Ismail","year":"2012","journal-title":"Tikrit J Dent Sci"},{"key":"R12-20240904","first-page":"1368","article-title":"Evaluation of antimicrobial activity of curcuminoids isolated from turmeric","volume":"3","author":"Singh","year":"2012","journal-title":"Int J Pharm Life Sci"},{"key":"R13-20240904","first-page":"27","article-title":"The difference of antibacterial effect of neem leaves and stick extracts","volume":"7","author":"Siswomihardjo","year":"2007","journal-title":"Int Chin J Dent"},{"key":"R14-20240904","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.3390\/molecules13081599","article-title":"Composition and applications of Aloe vera leaf gel","volume":"13","author":"Hamman","year":"2008","journal-title":"Molecules"},{"key":"R15-20240904","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.joen.2010.10.004","article-title":"The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris","volume":"37","author":"Dai","year":"2011","journal-title":"J Endod"},{"key":"R16-20240904","first-page":"416","article-title":"Comparative antimicrobial activity of Aloe vera gel on microorganisms of public health significance","volume":"1","author":"Shahzad","year":"2009","journal-title":"Pharmacologyonline"},{"key":"R17-20240904","doi-asserted-by":"crossref","first-page":"246","DOI":"10.4103\/0972-0707.97949","article-title":"Evaluation of antimicrobial efficacy of Aloe vera and its effectiveness in decontaminating gutta percha cones","volume":"15","author":"Athiban","year":"2012","journal-title":"J Conserv Dent"},{"key":"R18-20240904","doi-asserted-by":"crossref","first-page":"302","DOI":"10.9735\/0975-5276.4.8.302-307","article-title":"Antibacterial activity of ocimum species and their phytochemical and antioxidant potential","volume":"4","author":"Prasad","year":"2012","journal-title":"Int J Microbiol Res"},{"key":"R19-20240904","first-page":"366","article-title":"Comparative evaluation of the efficacy of three antioxidants versus NaOCl and EDTA:Used for root canal irrigation in smear layer removal-SEM study","volume":"7","author":"Bhargava","year":"2015","journal-title":"Int J Pharm Pharm Sci"},{"key":"R20-20240904","doi-asserted-by":"crossref","first-page":"459","DOI":"10.4103\/ejd.ejd_56_18","article-title":"Endodontic irrigants:Different methods to improve efficacy and related problems","volume":"12","author":"Dioguardi","year":"2018","journal-title":"Eur J Dent"},{"key":"R21-20240904","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1747-4477.2010.00266.x","article-title":"Evaluation of the antimicrobial activities of chlorhexidine gluconate, sodium hypochlorite and octenidine hydrochloride in vitro","volume":"39","author":"Tirali","year":"2013","journal-title":"Aust Endod J"},{"key":"R22-20240904","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.joen.2007.01.019","article-title":"Effects of short-term chemical disinfection of gutta-percha cones:identification of affected microbes and alterations in surface texture and physical properties","volume":"33","author":"Pang","year":"2007","journal-title":"J Endod"},{"key":"R23-20240904","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1365-2591.2005.00940.x","article-title":"Effects of 2% chlorhexidine and 5.25% sodium hypochlorite on gutta-percha cones studied by atomic force microscopy","volume":"38","author":"Valois","year":"2005","journal-title":"Int Endod J"},{"key":"R24-20240904","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1097\/01.don.0000158012.01520.e5","article-title":"Structural effects of sodium hypochlorite solutions on gutta-percha cones:Atomic force microscopy study","volume":"31","author":"Valois","year":"2005","journal-title":"J Endod"},{"key":"R25-20240904","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1097\/00004770-200310000-00015","article-title":"The crystallization of sodium hypochlorite on gutta-percha cones after the rapid-sterilization technique:An SEM study","volume":"29","author":"Short","year":"2003","journal-title":"J Endod"},{"key":"R26-20240904","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.joen.2005.08.002","article-title":"A comparison of cohesive strength and stiffness of Resilon and gutta-percha","volume":"32","author":"Williams","year":"2006","journal-title":"J Endod"},{"key":"R28-20240904","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/0030-4220(82)90468-6","article-title":"Antibacterial activity of gutta-percha cones attributed to the zinc oxide component","volume":"53","author":"Moorer","year":"1982","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R29-20240904","doi-asserted-by":"crossref","first-page":"376","DOI":"10.4103\/ijdr.IJDR_556_17","article-title":"Comparative evaluation of various herbal and synthetic solutions on disinfection of gutta-percha:An in vitro study","volume":"31","author":"Shailaja","year":"2020","journal-title":"Indian J Dent Res"},{"key":"R30-20240904","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1590\/S1517-83822009000400023","article-title":"Isolation, Purification and Evaluation of Antibacterial Agents from Aloe vera","volume":"40","author":"Lawrence","year":"2009","journal-title":"Braz J Microbiol"},{"key":"R31-20240904","doi-asserted-by":"crossref","first-page":"293","DOI":"10.4103\/jcd.jcd_75_21","article-title":"A proposed classification system for herbal endodontic irrigants","volume":"24","author":"Kale","year":"2021","journal-title":"J Conserv Dent"}],"container-title":["Journal of Conservative Dentistry and Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/JCDE.JCDE_300_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:52:56Z","timestamp":1786647176000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/JCDE.JCDE_300_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jcde.jcde_300_23","relation":{},"ISSN":["2950-4716","2950-4708"],"issn-type":[{"value":"2950-4716","type":"print"},{"value":"2950-4708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"2023-11-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}