{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:30:06Z","timestamp":1786649406291,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study aimed to compare the remineralizing efficacy of strontium-doped bioactive glass, BioMin, and NovaMin containing dentifrices on artificial white spot lesions (WSLs) after chlorhexidine (CHX) pretreatment using energy-dispersive X-ray analysis (EDAX).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methodology:<\/jats:title>\n                    <jats:p>Twenty-four samples of maxillary first premolars extracted for orthodontic purposes were selected. Artificial WSLs were produced by immersing the samples in a prepared demineralizing solution for 3 days. All the samples were pretreated with CHX and divided into four groups and six samples each. Group A treated with strontium-doped bioactive glass, Group B with BioMin, Group C with NovaMin, and Group D with artificial saliva as the control group for 14 days. pH-cycling model was used to simulate the oral cavity changes. EDAX was used to record the values at baseline, demineralization, and after remineralization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis:<\/jats:title>\n                    <jats:p>\n                      Data were analyzed using one-way ANOVA (\n                      <jats:italic toggle=\"yes\">post hoc<\/jats:italic>\n                      ), followed by unpaired\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test and Scheffe tests with Statistical Package for the Social Sciences version 16.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Strontium-doped bioactive glass exhibited a greater mineral regain compared to BioMin, NovaMin, and control groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Strontium-doped bioactive glass has enhanced mineral deposition on carious teeth and may provide an alternative clinical strategy for remineralizing early enamel lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcde.jcde_305_24","type":"journal-article","created":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T15:28:05Z","timestamp":1725722885000},"page":"925-929","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Comparative analysis of remineralizing efficacy of strontium-doped bioactive glass, BioMin, and NovaMin containing dentifrice on artificial white spot lesions after chlorhexidine pretreatment - An in vitro study"],"prefix":"10.4103","volume":"27","author":[{"given":"G.","family":"Nandhini","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jemima Shalini","family":"Samraj","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Mohamed","family":"Anish","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil Kumar","family":"Ramachandran","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandrasekaran","family":"Nirmala","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. F. Luke","family":"Denis","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,7]]},"reference":[{"key":"R2-20260427","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4103\/0972-0707.124136","article-title":"Enamel remineralization assessment after treatment with three different remineralizing agents using surface microhardness: An in vitro study","volume":"17","author":"Shetty","year":"2014","journal-title":"J Conserv Dent"},{"key":"R3-20260427","doi-asserted-by":"crossref","first-page":"457","DOI":"10.4103\/JCD.JCD_259_20","article-title":"Comparative evaluation of remineralizing potential of commercially available agents MI paste, Remin pro, and Clinpro using scanning electron microscope and energy dispersive X-ray: An in vitro 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