{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T13:39:27Z","timestamp":1788961167425,"version":"build-2803163510"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>Diabetes mellitus (DM) affects an estimated 100 million Indians, ranking second globally in diabetic prevalence. Despite this, the correlation between DM and specific pulpal diagnoses remains underexplored. This study compares pulpal conditions in DM patients and nondiabetic controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Designs:<\/jats:title>\n                    <jats:p>The study was started after taking ethical approval.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods:<\/jats:title>\n                    <jats:p>Two thousand and five hundred and sixty teeth were examined over 4 months at the institute, evenly distributed between diabetic and nondiabetic cases, we assessed diagnoses \u2013 normal pulp, reversible pulpitis (RP), symptomatic irreversible pulpitis, asymptomatic irreversible pulpitis, pulp necrosis (PN), missing teeth (MT), and root canal-treated teeth (RCT). Statistical analysis used the Chi-square test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>PN and MT prevalence in DM patients significantly exceeded the control group. Conversely, the control group showed higher RP prevalence in the older subgroup.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>PN prevalence was higher in diabetics, suggesting reduced pulp sensitivity in individuals over 60 years. This diminished sensitivity might lead to delayed dental treatment, increasing PN prevalence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcde.jcde_309_23","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T08:00:21Z","timestamp":1718784021000},"page":"755-759","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["An exploratory study to understand the relationship between diabetes and various pulpal conditions: An Indian perspective"],"prefix":"10.4103","volume":"27","author":[{"given":"Shivangi M.","family":"Pujara","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreya A.","family":"Khanna","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krupali D.","family":"Kalena","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhaval H.","family":"Jobanputra","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Shree M.P. Shah Government Medical College, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena H.","family":"Jobanputra","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish N.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Shree M.P. Shah Government Medical College, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"R2-20260507","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S2213-8587(23)00119-5","article-title":"Metabolic non-communicable disease health report of India: The ICMR-INDIAB national cross-sectional study (ICMR-INDIAB-17)","volume":"11","author":"Anjana","year":"2023","journal-title":"Lancet Diabetes Endocrinol"},{"key":"R3-20260507","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.4103\/ijo.IJO_1627_21","article-title":"Epidemiology of type 2 diabetes in India","volume":"69","author":"Pradeepa","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"R4-20260507","author":"Amit","year":"2019","journal-title":"Diabetes Mellitus"},{"key":"R5-20260507","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1021\/acsptsci.2c00122","article-title":"Diabetes and its complications","volume":"5","author":"Matoori","year":"2022","journal-title":"ACS Pharmacol Transl Sci"},{"key":"R6-20260507","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.2147\/DMSO.S318972","article-title":"Oral health messiers: Diabetes mellitus relevance","volume":"14","author":"Ahmad","year":"2021","journal-title":"Diabetes Metab Syndr Obes"},{"key":"R7-20260507","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/idh.12586","article-title":"Knowledge of bidirectional relationship between diabetes and periodontal disease among diabetes patients: A systematic review","volume":"21","author":"Maia","year":"2023","journal-title":"Int J Dent Hyg"},{"key":"R8-20260507","doi-asserted-by":"crossref","first-page":"540.","DOI":"10.3390\/jcm9020540","article-title":"Apical periodontitis and diabetes mellitus type 2: A systematic review and meta-analysis","volume":"9","author":"P\u00e9rez-Losada","year":"2020","journal-title":"J Clin Med"},{"key":"R9-20260507","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.joen.2014.12.024","article-title":"Glycated hemoglobin levels and prevalence of apical periodontitis in type 2 diabetic patients","volume":"41","author":"S\u00e1nchez-Dom\u00ednguez","year":"2015","journal-title":"J Endod"},{"key":"R10-20260507","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.joen.2015.10.020","article-title":"A prospective clinical pilot study on the level of matrix metalloproteinase-9 in dental pulpal blood as a marker for the state of inflammation in the pulp tissue","volume":"42","author":"Mente","year":"2016","journal-title":"J Endod"},{"key":"R11-20260507","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.joen.2021.11.001","article-title":"Altered prevalence of pulp diagnoses in diabetes mellitus patients: A retrospective study","volume":"48","author":"Gonzalez Marrero","year":"2022","journal-title":"J Endod"},{"key":"R12-20260507","doi-asserted-by":"crossref","first-page":"107839.","DOI":"10.1016\/j.diabres.2019.107839","article-title":"IDF diabetes atlas: Diabetes and oral health \u2013 A two-way relationship of clinical importance","volume":"157","author":"Borgnakke","year":"2019","journal-title":"Diabetes Res Clin Pract"},{"key":"R13-20260507","doi-asserted-by":"crossref","first-page":"5907195.","DOI":"10.1155\/2019\/5907195","article-title":"Diabetes: Oral health related quality of life and oral alterations","volume":"2019","author":"Cervino","year":"2019","journal-title":"BioMed research international"},{"key":"R14-20260507","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1089\/dia.2014.0018","article-title":"Glycemic control among individuals with self-reported diabetes in India \u2013 The ICMR-INDIAB study","volume":"16","author":"Unnikrishnan","year":"2014","journal-title":"Diabetes Technol Ther"},{"key":"R15-20260507","doi-asserted-by":"crossref","first-page":"465","DOI":"10.5001\/omj.2012.111","article-title":"HbA1c levels among primary healthcare patients with type 2 diabetes mellitus in Oman","volume":"27","author":"Al-Lawati","year":"2012","journal-title":"Oman Med J"},{"key":"R16-20260507","first-page":"5","article-title":"Insidious role of diabetes mellitus on nerves and dental pulp tooth innervation and diabetes mellitus type 2","volume":"13","author":"Fenn","year":"2019","journal-title":"J Clin Diagn Res"},{"key":"R17-20260507","doi-asserted-by":"crossref","first-page":"9440.","DOI":"10.3390\/app11209440","article-title":"Histological Aspects Regarding Dental Pulp of Diabetic Patients","volume":"11","author":"Pu\u015fca\u015fu","year":"2021","journal-title":"Applied Sciences"},{"key":"R18-20260507","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/0003-9969(92)90061-C","article-title":"Effect of ageing on responses of nerve fibres to pulpal inflammation in rat molars analysed by quantitative immunocytochemistry","volume":"37","author":"Swift","year":"1992","journal-title":"Arch Oral Biol"},{"key":"R19-20260507","doi-asserted-by":"crossref","first-page":"323","DOI":"10.4103\/0972-0707.101888","article-title":"Incidence of post-operative pain after single visit and multiple visit root canal treatment: A randomized controlled trial","volume":"15","author":"Singh","year":"2012","journal-title":"J Conserv Dent"},{"key":"R20-20260507","doi-asserted-by":"crossref","first-page":"348","DOI":"10.4103\/jcd.jcd_216_21","article-title":"Incidence of postoperative pain after single-visit and multiple-visit root canal therapy: A randomized controlled trial","volume":"24","author":"Gupta","year":"2021","journal-title":"J Conserv Dent"},{"key":"R21-20260507","doi-asserted-by":"crossref","first-page":"319","DOI":"10.4103\/0972-0707.101886","article-title":"Molecular identification of an Enterococcus faecalis endocarditis antigen efaA in root canals of therapy-resistant endodontic infections","volume":"15","author":"Preethee","year":"2012","journal-title":"J Conserv Dent"},{"key":"R22-20260507","doi-asserted-by":"crossref","first-page":"430","DOI":"10.4103\/JCD.JCD_326_19","article-title":"PCR-based detection of three anaerobic bacteria associated with endodontic-periodontic lesions in type-2 diabetic and nondiabetic subjects","volume":"22","author":"Nair","year":"2019","journal-title":"J Conserv Dent"},{"key":"R23-20260507","doi-asserted-by":"crossref","first-page":"392","DOI":"10.4103\/jcd.jcd_18_22","article-title":"Comparison of postoperative pain following single-visit and two-visit root canal therapy in controlled diabetic patients with irreversible pulpitis: A randomized control trial","volume":"25","author":"Anagha","year":"2022","journal-title":"J Conserv Dent"},{"key":"R24-20260507","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.joen.2021.11.001","article-title":"Altered prevalence of pulp diagnoses in diabetes mellitus patients: A retrospective study","volume":"48","author":"Marrero","year":"2022","journal-title":"Journal of endodontics"}],"container-title":["Journal of Conservative Dentistry and Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/JCDE.JCDE_309_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:37:44Z","timestamp":1787067464000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/JCDE.JCDE_309_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,19]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jcde.jcde_309_23","relation":{},"ISSN":["2950-4716","2950-4708"],"issn-type":[{"value":"2950-4716","type":"print"},{"value":"2950-4708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,19]]},"assertion":[{"value":"2023-12-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}}]}}